Zinc oil preparation for treating burn and scald and preparation process thereof

A technology of preparation and zinc oil, which is applied in the field of external preparations containing traditional Chinese medicine extracts and its preparation, can solve the problems of poor curative effect, poor air permeability, inconvenient coating, etc., and achieve novel dosage forms, easy acceptance, and simple preparation methods Effect

Inactive Publication Date: 2005-01-26
戴海华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some existing other scab-removing medicines containing traditional Chinese medicine ingredients include ointments, pastes and powders, etc., most of which have disadvantages such as inconvenient application, poor air permeability, and poor curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1, the formulation of the raw materials of the preparation, by weight: 5 parts of Galla chinensis, 5 parts of raw rhubarb, 2.5 parts of Sanqi, 5 parts of licorice, 10 parts of zinc oxide, 1 part of dyclonine, and yellow petrolatum, lanolin 71.5 parts of matrix composed of paraffin oil.

[0013] Preparation method: 1. Weigh gallnut, raw rhubarb, notoginseng and licorice in a container according to the above ratio, and add 75% concentration ethanol twice the volume of the above mixture, and soak naturally for 7 days; 2. filter out the soaking solution, reduce Volatilize under pressure to remove ethanol to obtain a concentrated solution containing the above-mentioned traditional Chinese medicine ingredients; ③ put the concentrated solution in a sterilized container, and add dyclonine, dry heat sterilized Bacterial zinc oxide powder, vaseline and lanolin, mix evenly, then add liquid paraffin and mix until semi-solid; ④Separate packaging.

Embodiment 2

[0014] Example 2, the raw material formula of the preparation, by weight: 6 parts of Galla chinensis, 6 parts of raw rhubarb, 3 parts of Sanqi, 6 parts of licorice, 10 parts of zinc oxide, 1 part of dyclonine, and made of vaseline, lanolin And 68 parts of bases composed of paraffin oil.

[0015] The preparation method is the same as in Example 1.

Embodiment 3

[0016] Embodiment 3, the raw material formula of preparation, by weight ratio is: gallnut 4 parts, raw rhubarb 4 parts, notoginseng 2 parts, licorice 4 parts, zinc oxide 10 parts, dyclonine 1 part, and by Vaseline, lanolin 75 parts of the matrix composed of paraffin oil.

[0017] The preparation method is the same as in Example 1.

[0018] The preparations prepared in the above three examples were used for the treatment of burn wounds, and 152 clinical cases all achieved good results. In particular, superficial II° wound swelling subsided, local inflammatory reaction was not obvious, the inner layer of gauze was dry after 1-2 dressing changes, no obvious pain and bleeding when removed, and the surface was smooth without scars; deep II° wound superficial necrosis The liquefaction is fast, the purulent secretion is easy to see through the inner layer of gauze and there is little secretion accumulation, the local inflammatory reaction is mild, and the necrosis is removed after 2...

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PUM

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Abstract

The invention provides a zinc oil preparation for treating burn and scald and preparation process thereof, wherein the preparation comprises (by weight proportion) schisandra fruit 4-6 parts, rheum officinale 4-6 parts, notoginseng 2-3 parts, licorice root 4-6 parts, zinc oxide 10 parts, dyclonine 1 part, and ground substance 75-68 parts.

Description

technical field [0001] The invention belongs to pharmaceutical preparations, in particular to an external preparation containing traditional Chinese medicine extracts for treating burn wounds and a preparation method thereof. Background technique [0002] The key to burn treatment is wound treatment. At present, the medication for burn wounds can be roughly divided into antibacterial drugs and scab-removing drugs. The former is represented by silver sulfadiazine, and cream or paste is mostly used, which can prevent wound infection and prevent wound deepening, but silver sulfadiazine cream has impregnation effect on wound tissue, and frequent dressing changes are required after application, and silver sulfadiazine The side effect of the strong bacteriostatic effect is that the sub-infection level bacteria that are beneficial to wound healing will be lost, which is not conducive to wound healing. Commonly used scab-removing drugs such as comfrey oil, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61P17/02
Inventor 戴海华
Owner 戴海华
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