Use of centellosic acid derivative in preparation of medicines for diseases of cardio-cerebral blood vessels

A technology for cerebrovascular disease and asiatic acid, applied in the field of application of asiatic acid derivatives in the preparation of drugs for the prevention and treatment of cardiovascular and cerebrovascular diseases, can solve the problems of unsatisfactory treatment effect of ischemic encephalopathy, and achieve remarkable results , the effect of reducing the infarct size

Inactive Publication Date: 2005-02-23
北京苏里曼医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment effect of ischemic encephalopathy is not satisfa

Method used

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  • Use of centellosic acid derivative in preparation of medicines for diseases of cardio-cerebral blood vessels
  • Use of centellosic acid derivative in preparation of medicines for diseases of cardio-cerebral blood vessels

Examples

Experimental program
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Effect test

Embodiment 1

[0020] The preparation of embodiment 1 capsule

[0021] Take 500 grams of asiatic acid or madecassic acid raw material, 1000 grams of medicinal starch, stir evenly, put into No. 0 capsules, 0.3 grams per capsule, take 2 capsules each time, three times a day.

Embodiment 2

[0022] Example 2 Tablet Preparation

[0023] Take 500 grams of asiatic acid or madecassic acid asiatic acid raw material, 500 grams of medicinal starch, stir well, granulate with appropriate amount of ethanol, after granulation, compress into tablets, 0.2 grams per tablet, orally, 2 tablets each time, three times a day .

Embodiment 3

[0024] The preparation of embodiment 3 granules

[0025] Take 200 grams of asiatic acid or madecassic acid raw materials, 4000 grams of medicinal starch, and 800 grams of sucrose, mix well, granulate with appropriate amount of ethanol, dry, granulate, and divide into packages to obtain, 5 grams per bag, 1 ounce each time bag, three times a day.

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Abstract

An application of the asiaticic acid derivative in preparing the medicine in the form of capsule, tablet, particle, or injection for preventing and treating cardiovascular and cerebrovascular diseases is disclosed.

Description

Technical field: [0001] The invention relates to the use of asiatic acid derivatives in the preparation of drugs for preventing and treating cardiovascular and cerebrovascular diseases. Background technique: [0002] Centella asiatica (L.) Urban is a plant of the genus Centella asiatica, which is widely distributed in the south of the Yangtze River Basin. The whole herb is used as medicine. Centella asiatica has a history of more than 2,000 years in my country for its external and oral administration. It has the functions of clearing away heat and dampness, detoxifying and reducing swelling. It is suitable for damp-heat jaundice, heatstroke and diarrhea, sand and blood, carbuncle and sore, and injury from falls. [0003] The chemical composition of Centella asiatica is mainly triterpenoids, such as asiaticoside, madecassoside, brahmoside, brahminoside, and ginseng Pentacyclic triterpene-type ester glycosides such as thankuni-side, isothankuniside, and centelloside. Cent...

Claims

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Application Information

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IPC IPC(8): A61K31/56A61K31/704A61P9/10
Inventor 崔福贵
Owner 北京苏里曼医药科技有限公司
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