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Application of ferriferrous oxide particle in preparation of tumour heating treatment auxiliary drug

A technology of ferric oxide and microparticles, which is applied in the direction of antineoplastic drugs, drug combinations, heavy metal active ingredients, etc. It can solve the problem of undetermined suspension matrix composition and concentration of iron oxide components, and achieve the effect of improving the therapeutic effect

Inactive Publication Date: 2005-09-21
CHINA JAPAN FRIENDSHIP HOSPITAL
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Problems solved by technology

[0003] So far, magnetic particles have been used in a variety of industries, and there is currently a nano-scale iron ferric oxide particle used for medical magnetic resonance imaging enhancement, and there are also some iron oxides used in tumor enhancement. use as an adjunct to warm therapy, but the optimal composition of iron oxides and the composition and concentration of the suspending matrix have not been determined

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  • Application of ferriferrous oxide particle in preparation of tumour heating treatment auxiliary drug
  • Application of ferriferrous oxide particle in preparation of tumour heating treatment auxiliary drug
  • Application of ferriferrous oxide particle in preparation of tumour heating treatment auxiliary drug

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Embodiment Construction

[0019] The invention uses ferric oxide microparticles to prepare the auxiliary drug for tumor heating therapy, injects it into the tumor area, and then puts the tumor area under an alternating magnetic field of a certain frequency, the microparticles will absorb the energy of the magnetic field to generate heat, and Raise the temperature of the surrounding tissue, so as to achieve the purpose of killing tumor cells by raising the temperature of the tumor tissue.

[0020] In the embodiment of the present invention, nano-scale ferroferric oxide magnetic particles produced by Anhui Jinke Powder Co., Ltd. are selected. refer to figure 1 , magnified by 200,000 times in the figure, 1mm in the figure is equivalent to 5nm, and a large grid in the figure is 1.0cm. The average particle size of this magnetic particle is 9.2nm, and carboxymethyl cellulose solution is selected as the suspension matrix. Ferric oxide microparticles are used as an auxiliary drug for the preparation of tumor ...

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Abstract

The invention discloses the application of ferriferrous oxide particle in preparation of tumour heating treatment auxiliary drug, wherein suspending base material is employed to prepare suspending liquid from ferrosic oxide particles, wherein the suspending base material and the ferrosic oxide particles being, in each 1.0ml of suspension base material with the concentration of 0.2-5%, 10-120 mg of ferroferric oxide particles are charged, i.e. the concentration of the suspension solution is 10-120 mg / ml.

Description

technical field [0001] The present invention relates to the application of a compound, in particular to the application of ferric ferric oxide particles as an auxiliary drug for the preparation of tumor warming therapy. Background technique [0002] At present, there have been examples of injecting hot water into the tumor to heat up the tumor tissue in the tumor heating therapy. However, after the hot water is injected into the tumor tissue, the heat is absorbed by the surrounding tissue and then quickly cools down. To continue heating, it needs to be injected again, so trauma Larger size is not conducive to repeated treatment, and its effect is not good. It is an important technical task at present to seek new substances for the preparation of drugs for the auxiliary treatment of tumor warming. [0003] So far, magnetic particles have been used in various industries, and there is currently a nano-scale iron ferric oxide particle used for medical magnetic resonance imaging...

Claims

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Application Information

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IPC IPC(8): A61K33/26A61P35/00
Inventor 唐劲天赵天德刘轩洛小林夏启胜徐波
Owner CHINA JAPAN FRIENDSHIP HOSPITAL
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