Diagnostic decision support system and method of diagnostic decision support

A support system and diagnosis and treatment information technology, applied in the direction of diagnosis, medical automated diagnosis, diagnosis record/measurement, etc., to achieve the effect of high-precision diagnosis support knowledge

Inactive Publication Date: 2005-09-28
HITACHI LTD
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Problems solved by technology

[0011] However, this premise does not always hold

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  • Diagnostic decision support system and method of diagnostic decision support
  • Diagnostic decision support system and method of diagnostic decision support
  • Diagnostic decision support system and method of diagnostic decision support

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Embodiment Construction

[0031] FIG. 1 is a diagram showing a configuration example of a diagnosis support system of the present invention. The diagnostic support system 111 of the present invention is mainly constituted by an electronic computer such as a so-called personal computer. The processor 1 , the memory 2 , the input device 3 , the display device 4 and the external storage device 10 are connected to the system bus 5 . In the external storage device 10, a medical information database 11 stores the medical information of a plurality of individuals (diagnosed persons); a gene polymorphism information database 12 stores the gene polymorphisms of a plurality of individuals (diagnosed persons) Relevant information; haplotype information database 14, based on the information of the genetic polymorphism information database 12, infers the position of the haplotype block, and infers the haplotype frequency of the population and the haplotype pattern of the individual for each haplotype block, Store ...

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Abstract

There is provided a system performing high-accuracy diagnostic decision support in consideration of the influence of a haplotype block and a genetic structure. Haplotype block inference means 13 infers the positions of haplotype blocks, and analyzes each of the haplotype blocks to infer a haplotype pattern of individuals with high accuracy. Genetic structure inference means 15 performs clustering the individuals on the basis of the haplotype pattern to divide a population into some subpopulations, and removes the influence of a genetic structure existing in the population. A genetic structure information database 16 and a clinical information database 11 are used to analyze association of clinical information with genetic information for providing high-accuracy diagnostic decision support knowledge. On the basis of the diagnostic decision support knowledge obtained by analyzing the association of clinical information with genetic information, risk calculation means 19 calculates a risk that a predetermined individual is affected by disease.

Description

technical field [0001] The present invention relates to a diagnosis support system and a diagnosis support method, which analyze the correlation between clinical information and gene information, extract and present clinically useful information. Background technique [0002] The Human Genome Project has roughly completed the sequence determination and entered the era of post-sequencing. In the future, it is expected that the huge amount of accumulated genetic information will be effectively used in medicine. If the research on the relationship between genes and diseases is developed, the risk of disease onset can be predicted based on the individual's genotype, and disease prevention, early detection, and treatment can be carried out according to the individual's genetic quality. To achieve this, it is necessary to analyze the correlation between clinical information and genetic information. [0003] As one of the powerful methods for analyzing the correlation between cli...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00C12Q1/68G01N33/48G01N33/50G06FG06Q50/00G06Q50/10G16B20/20G16B20/40G16B40/00G16H50/20
CPCG06Q50/24G06F19/24G06F19/3431C12Q1/6883G06F19/18G06F19/345G16H50/30G16H50/20G16B20/00G16B40/00G16B20/20G16B20/40
Inventor 齐藤聪光山训伴秀行
Owner HITACHI LTD
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