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Tranquilizing wild jujube seed dripping pill and its preparing method

A technology of zaoren calming the nerves and dropping pills, applied in the directions of pill delivery, pharmaceutical formulations, nervous system diseases, etc., can solve problems such as adverse overall health level, low dissolution rate, unfavorable improvement of patients' ability to seek medical treatment, etc., and is conducive to labor protection. and environmental protection, accelerated dissolution and absorption, and improved bioavailability

Inactive Publication Date: 2005-10-19
北京正大绿洲制药有限公司
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  • Summary
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
The drug content of granules is also low, and it is inconvenient to take
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Zaoren Anshen dripping pills of the present invention will be further described.

[0030] Group 1: Tests with a single matrix

[0031] 1. Preparation of the medicinal extract: According to [Preparation Method 1], the dry powder of the extract containing the active pharmaceutical ingredients of 3 traditional Chinese medicines, such as Jujube Seed, Salvia Miltiorrhiza, and Schisandra, was first prepared for use;

[0032] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. According to the process given in [Preparation Method] 4-7, Zaoren Anshen Dropping Pills of different specifications can be obtained.

[0035] [...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, tranquilizign wild jujube seed dripping pill, used in treating insomnia, amnesia, dizziness, headache, etc. caused by heart, liver and blood deficiency and neurosism. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost, and its production process has no pollution. The tranquilizign wild jujube seed dripping pill is prepared with three kinds of Chinese medicinal materials of wild jujube seed, red sage and schisandra and medicine carrier as matrix.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the function of invigorating the heart, nourishing the liver, calming the nerves and improving intelligence, and is used for the treatment of insomnia, forgetfulness, dizziness, headache and other diseases caused by neurasthenia. An oral preparation of a pharmaceutical composition prepared from three traditional Chinese medicines as raw materials. Background technique [0002] Zaoren Anshen Granules prepared according to the preparation method given in the ministerial drug standard WS3-B-2164-96 has the functions of invigorating the heart, nourishing the liver, calming the nerves and improving intelligence, and is used for insomnia caused by heart and liver blood deficiency and neurasthenia Oral granules for the treatment of forgetfulness, dizziness, headache and other diseases have been clinically verified and have definite curative effects. It is a commonly used drug for clini...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P25/04A61P25/20
Inventor 曲韵智
Owner 北京正大绿洲制药有限公司
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