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Combination of effective parts for curing chronic hepatitis, preparation and usage

A technology of effective parts and compositions, applied in the field of effective part compositions for the treatment of chronic hepatitis and its preparation and application

Inactive Publication Date: 2006-02-01
南京宇道科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching for relevant information, there are no pharmaceutical companies or pharmaceutical research institutions at home and abroad that have extracted effective parts of Bupleurum, Scutellaria baicalensis and Glycyrrhiza glycosides, total flavonoids of scutellaria baicalensis and total glycosides of licorice to form a group of effective parts, and produce and process them into suitable pharmaceutical preparations For the treatment of liver disease

Method used

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  • Combination of effective parts for curing chronic hepatitis, preparation and usage
  • Combination of effective parts for curing chronic hepatitis, preparation and usage
  • Combination of effective parts for curing chronic hepatitis, preparation and usage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Take a certain proportion of the effective fractions composed of total glucosides of Bupleurum glycosides, total flavonoids of Scutellaria baicalensis and total glycosides of glycyrrhizin, dry, pulverize, pass through an 80 mesh sieve, mix them with microcrystalline cellulose through an 80 mesh sieve, and make granules with 95% ethanol , air-dried, sieved with 20 meshes, filled with capsules, polished and packaged.

[0032] Prescription Composition (1000 Capsules) Bupleuradin 30g

[0033] Total Flavonoids of Scutellaria baicalensis 70g

[0034] Glycyrrhizin 50g

[0035] Microcrystalline Cellulose 75g

[0036] Its technological process sees accompanying drawing 1 of specification sheet.

Embodiment 2

[0038] Take a certain proportion of the active fraction group composed of total glucosides of Bupleurum, baicalin and glycyrrhizin, dry, pulverize, pass through an 80 mesh sieve, and mix evenly with microcrystalline cellulose and sodium carboxymethyl starch through an 80 mesh sieve, and mix with 5 Granules made of %PVP, air-dried, granulated with a 20-mesh sieve, added with magnesium stearate, and compressed into tablets.

[0039] Prescription composition: (1000 tablets) Bupleurum glycosides 10g

[0040] Baicalin 30g

[0041] Glycyrrhizin 4g

[0042] Sodium carboxymethyl starch 5g

[0043] Microcrystalline Cellulose 73g

[0044] Magnesium Stearate 2g

[0045] Its technological process is shown in accompanying drawing 2 of specification sheet.

[0046] The following pharmacological experiment results illustrate its drug effect:

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Abstract

A Chinese medicine in the form of tablet, capsule, softgel, pill, etc for treating chronic hepatism and chronic hepatitis is prepared from bupleurum root, scutellaria root and liquorice root through extracting their active components, mixing them with proper excipient, and shaping.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine development, and relates to a composition of effective parts for treating chronic hepatitis and its preparation and application, in particular to total glycosides of Bupleurum glycosides, total flavonoids of Scutellaria baicalensis and The active part composition composed of total glycyrrhizin and its preparation and its application in the preparation of drugs with the functions of anti-hepatitis virus, liver protection and enzyme reduction, and immune function regulation. Background technique: [0002] Chronic hepatitis refers to liver inflammation, abnormal histological and biochemical signs that persist for more than 6 months, and the condition does not improve significantly, or there are active inflammatory changes in the liver. It is not a single disease, but includes chronic liver diseases caused by various etiologies. Chronic hepatitis can be caused by viruses, drugs, alcohol a...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K36/484A61K36/233A61P1/16A61P31/12
Inventor 史美耿阮锦满王永毅钱世祥姚小燕
Owner 南京宇道科技开发有限公司
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