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Rheumatism treating medicine and its prepn process

A technology for rheumatism and medicine, which is applied in the field of medicine for treating rheumatism and its preparation, can solve problems such as joint dysfunction, joint destruction and unsatisfactory deformity effect, and achieves the effect of being convenient for long-term administration, widely distributed and inhibiting joint destruction

Inactive Publication Date: 2006-10-18
THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies have shown that these three tripterygium medicinal preparations can significantly reduce joint pain and eliminate joint swelling, but are still not satisfied with the effect of improving joint dysfunction, joint destruction and deformity, and inhibit gonad function, gastrointestinal reactions and liver function damage, etc. side effects also affect the further application

Method used

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  • Rheumatism treating medicine and its prepn process
  • Rheumatism treating medicine and its prepn process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Recipe: 40kg Kunming Begonia, 20kg Dipsacus.

[0028] Preparation method (mixture): Submerge Kunming Begonia in water, first fry for 3.5-7 hours, then add Dipsacus and fry for 0.5-1 hour, filter, concentrate the filtrate to about 90,000 ml, add 0.1% ethylparaben, 0.3 % sodium benzoate was stirred and dissolved, allowed to cool, adjusted to the full amount of the liquid medicine, filtered, and subpackaged after passing the test. Prepare 90,000 milliliters of oral liquid (mixture).

Embodiment 2

[0030] Recipe: 60kg Kunming Begonia, 20kg Dipsacus.

[0031] Preparation method (capsule): Submerge Kunming Begonia in water, first fry for 3.5-7 hours, then add Dipsacus and fry for 0.5-1 hour, filter, concentrate under reduced pressure, the pressure is -0.08Mpa, the temperature is 50°C-80°C, Concentrate and measure the clear paste with a relative density of 1.18-1.20, dry it at 65°C to obtain a dry extract, crush it, pass through a 60-mesh sieve, and pack into No. 0 capsules. Prepared into capsules.

Embodiment 3

[0033] Recipe: 20kg Kunming Begonia, 20kg Dipsacus.

[0034] Preparation method (tablet): Submerge Kunming Begonia in water, first fry for 3.5-7 hours, then add Dipsacus and fry for 0.5-1 hour, filter, concentrate under reduced pressure, the pressure is -0.08Mpa, the temperature is 50°C-80°C , concentrate and measure the clear paste with a relative density of 1.18-1.20, dry it at 65°C to obtain a dry extract, crush it, pass through a 100-mesh sieve, weigh it, add an appropriate proportion of sodium carboxymethyl starch, mix well, granulate with ethanol, and dry , whole grains, weighed, added with appropriate proportion of magnesium stearate, compressed into tablets, coated with water-soluble film, packaged for storage. Prepared as tablets.

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Abstract

The present invention is one kind of rheumatism treating medicine and its preparation process. The rheumatism treating medicine is prepared with tripterygium in 1-7 weight portions and himalayan teasel in 1 weight portions; and the preparation process includes the following steps: soaking tripterygium, decocting tripterygium for 3.5-7 hr, adding himalayan teasel before further decoction of other 0.5-1 hr, filtering and further treatment to obtain the preparation in required form. The present invention has high curative effect on RA, AS, SLE, OA and other type of rheumatism, less toxic side effect, and simple preparation process.

Description

technical field [0001] The invention relates to a medicine for treating rheumatism and a preparation method thereof. technical background [0002] Rheumatism is a group of diseases involving the bones, joints, muscles and their soft tissues. Among them, rheumatoid arthritis (RA), ankylosing spondilitis (AS), systemic lupus erythematosus (SLE) and osteoarthritis (OA) are the most common Rheumatic diseases, all of which have clinical manifestations such as muscle, tendon, joint pain and joint swelling, are affecting hundreds of millions of people of all races around the world, causing huge losses to individuals, families and society. Countries around the world are seeking specific treatments Work with drugs. Non-steroidal anti-inflammatory drugs (such as indomethacin, etc.) are first-line drugs for the treatment of various rheumatic diseases, but they have no obvious effect on improving the condition and inhibiting joint damage, and their toxic side effects such as peptic ul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/08A61K9/10A61K36/37A61P19/02A61P29/00
Inventor 陈纪藩陈光星刘清平林昌松刘晓玲关彤
Owner THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE
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