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Method for extended storage of blood and blood components

一种血液成分、血液制品的技术，应用在含有效成分的医用配制品、医药配方、人或动物体的保存等方向，能够解决损坏血液组分、损坏全血和/或血液组分、没有保存全血和/或血液组分等问题，达到延长保存期、减少含量的效果

Inactive Publication Date: 2006-12-13
SAFETIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Each method has a number of disadvantages, including the fact that they are usually only suitable for one blood component and that the cleaning methods used can damage the blood component
In addition, the preservation method itself may damage blood components
Therefore, there is currently no suitable method for preserving whole blood and / or blood components that does not involve introducing potentially harmful chemicals into the body, nor does it involve damaging the whole blood and / or blood components themselves

Method used

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  • Method for extended storage of blood and blood components
  • Method for extended storage of blood and blood components
  • Method for extended storage of blood and blood components

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Embodiment Construction

[0036] The present invention provides a relatively nontoxic and reversible method of manipulating platelets and, optionally, other blood components. As noted above, the method of the present invention involves treatment with carbon monoxide in such a small amount that its toxicity is low enough to be tolerated by the body.

[0037] The present invention also provides a method of inhibiting the growth of bacteria in blood components by treatment with carbon monoxide, so that such methods can be used to prolong the storage life of these blood components. As detailed below, the present invention is preferably used to preserve platelets, which are particularly susceptible to infection by bacteria and other microorganisms, so the methods of the present invention are particularly applicable to platelets.

[0038] According to a preferred embodiment of the present invention, the whole blood provided by the donor is first separated into various components, and then, more preferably, o...

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PUM

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Abstract

A method for treatment of platelets, and optionally other blood components, which is relatively non-toxic and which is also reversible. The method of the present invention involves treatment with carbon monoxide, which in small amounts is sufficiently non-toxic to be tolerated by the body.

Description

[0001] This application is a divisional application, the international application number of the original application is PCT / IL03 / 00375, the Chinese national application number is 03810783.X, the application date is May 8, 2003, and the invention title is "long-term storage of blood and blood group method of scoring". technical field [0002] The present invention relates to methods for long-term storage and preservation of blood and blood components by treating blood and / or blood components with CO (carbon monoxide). Background technique [0003] Blood transfusion is an important therapeutic adjunct in modern medicine. It is the mainstay of treatment in the field of emergency medicine. So blood has been collected and stored in blood banks since the beginning of the twentieth century. Originally collected and stored as whole blood, blood collected from donors is now separated into specific components before being stored and ultimately used to treat patients. Store these b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/14A61K41/00A01N1/00A61J3/00
CPCA61K41/0009A01N1/0215A61K35/14A01N1/00A61K41/10
Inventor 马蒂亚胡·沙克拉
Owner SAFETIN
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