Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Dual high immunity immunoglobulin for anti reproduction of pig and breathing syndrome, second type cirque virus of pig

A technology of respiratory syndrome and immunoglobulin, applied in the field of double-linked hyperimmune immunoglobulin, can solve the problems of increased mortality in pig herds, mixed infection and infection of pigs' immunity, obstacles, etc., and achieves short course of treatment, good safety, Ease of use

Inactive Publication Date: 2007-05-09
张中洋
View PDF1 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, these two diseases often have mixed infections and cause immune disorders in the infected pigs, thereby causing secondary infections of other diseases (such as secondary infections of suis streptococcosis), causing a sharp increase in the mortality rate of pigs. Especially for farms and households that raise commercial pigs, it often leads to the consequences of annihilation
After the onset of the animal, only antibiotics or immunomodulatory preparations can be used to control the concurrent bacterial infection and improve the non-specific immune function of the animal body, which cannot fundamentally solve the problem

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] 1. Selection of immunized animals: The immunized animals of the present invention use strictly quarantined pigs and horses (mutes, donkeys) as immunized animals.

[0043] 2, the immunogen of the present invention is prepared by adding complete Freudian's adjuvant after getting cell culture, and cultivating porcine reproductive and respiratory syndrome virus with Marc-145 cells, and the virus calibration value reaches 10 6～8 . Porcine circovirus type 2 was cultivated with PK-15 cells, and the virus calibration value reached 10 5～6 , the two immunogens were mixed in a ratio of 1:2, and Freund's adjuvant was added according to the volume ratio of 1:1 as the immunogen to immunize animals; at the same time, the glycoside injection developed by Jilin Whale Elephant Animal Pharmaceutical Co., Ltd. was used as Immunopotentiator, 5ml / bottle, to increase antibody titer.

[0044] 3. The way of immunization is intradermal, subcutaneous or acupoint or intramuscular multi-point inj...

Embodiment 2

[0053] The immunogen of the present invention is prepared by taking cell culture and adding complete Freud's adjuvant after concentration, and cultivating porcine reproductive and respiratory syndrome virus with Marc-145 cells, and the virus calibration value reaches 10 6～8. Porcine circovirus type 2 was cultivated with PK-15 cells, and the virus calibration value reached 10 5～6 The two immunogens were mixed in a ratio of 2:1 and Freund's adjuvant was added according to the volume ratio of 1:1 to immunize animals as immunogens; at the same time, the glycoside injection developed by Jilin Whale Elephant Animal Pharmaceutical Co., Ltd. was used as Immunopotentiator, 5ml / bottle, to increase antibody titer.

[0054] Other steps are the same as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

An immunoglobulin for preventing the reproduction-respiration syndrome and gyrate virus B of hog is prepared from their immunogens through cell culture, concentrating and proportionally mixing it with complete Frennd's adjuvant. It features that the glycoside-peptide injection is used as its immunopotentiator.

Description

technical field [0001] The invention belongs to the field of biotechnology, and specifically relates to a dual hyperimmune immunoglobulin against porcine reproductive and respiratory syndrome and porcine type 2 circovirus. The international patent classification number is A61K39 / 395. Background technique [0002] Porcine reproductive and respiratory syndrome and porcine circovirus type 2 are new infectious diseases that seriously endanger the pig industry in my country in recent years. These two diseases come from imported pigs and are newly introduced diseases in our country. Since our country is currently a new epidemic area, the prevalence and harm of these two diseases in our country are also relatively serious. It often results in abortion of sows and death of piglets in litters. Huge losses have been caused to the pig industry. [0003] Porcine reproductive and respiratory syndrome (Porcine reproductive and respiratory syndrome, PRRS), also known as blue ear disease...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K39/395A61K39/295A61K39/39A61P31/12
Inventor 张中洋
Owner 张中洋
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com