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Method and apparatus for obtaining tissue micro tomography image and spectrum

A technique of tissue and spectroscopy, applied in the field of biomedical detection

Inactive Publication Date: 2007-05-16
UNIV OF SHANGHAI FOR SCI & TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

A major problem currently facing the new (fibre-optic) confocal microscope is that it only provides information on the morphological changes of tissue cells and nuclei

Method used

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  • Method and apparatus for obtaining tissue micro tomography image and spectrum
  • Method and apparatus for obtaining tissue micro tomography image and spectrum
  • Method and apparatus for obtaining tissue micro tomography image and spectrum

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Embodiment Construction

[0022] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0023] A device for obtaining tissue microtomography images and spectra, as shown in Figure 1, is characterized in that it includes:

[0024] A white light source 1 for providing illumination light;

[0025] A collimating lens 2 and a coupling lens 4 are used to adjust the illumination beam and the signal beam,

[0026] A fiber confocal system composed of a single-mode optical fiber 5 connected to a probe composed of a scanning device 6 and an imaging lens group 7, a scanning device 6 placed between the single-mode optical fiber 5 and the imaging lens group 7 of the probe;

[0027] The beam splitter 3 and the beam splitter 12 realize the separation of the backscattered signal light and the illumination light received by the optical fiber confocal system at the conjugate point of the fiber end face in the human tissue, and the separation of the signal l...

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Abstract

The invention relates to a method for obtaining the organism microscope chromatography image and spectrum based on optical fiber focus system, wherein the white light is the lighting resource; the focus system lights the organism and obtains the light signal carrying the organism signal; the invention uses two methods to receives the back toward scattering signal; via signal processing, the computer displays the chromatography image and spectrum of organism, and controls the scanning device, to compare the cell shape and spectrum of normal organism, to diagnose the cancer.

Description

technical field [0001] The present invention relates to a method and device for biomedical detection, in particular to the use of optical fiber confocal system to detect tissue backscattered signal light. Spectroscopy for early diagnosis of cancer. Background technique [0002] According to the survey report released by the World Health Organization in 2002, more than 6,000,000 people die of cancer worldwide every year, and more than 10,000,000 new cancer cases appear. One of the main reasons for the high morbidity and mortality of cancer is that the existing medical detection methods cannot or effectively detect or diagnose cancer at an early stage. It is necessary to develop non-invasive, in vivo and real-time technologies for early detection of cancer. Confocal reflectance microscopy can obtain the information of different slices in the range of hundreds of microns in the tissue through horizontal two-dimensional scanning and longitudinal one-dimensional scanning, and r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00G01N21/84
Inventor 陈家璧刘勇王成
Owner UNIV OF SHANGHAI FOR SCI & TECH