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Compound ciprofloxacin injection for animal and its preparing process

A technology of ciprofloxacin and ciprofloxacin lactate is applied in the directions of effective components of heterocyclic compounds, pill delivery, antibacterial drugs, etc., and can solve the problems of farmers' economic loss, unsatisfactory curative effect, and untimely treatment, etc. Achieve unique curative effect, good antibacterial effect, accurate dose effect

Inactive Publication Date: 2012-11-07
江西百思技术咨询有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Intestinal diseases of livestock and poultry are prone to onset, seriously affecting their growth, untimely treatment, high mortality, and causing huge economic losses to farmers
At present, the veterinary clinical treatment of livestock and poultry intestinal diseases is generally a single preparation, and most of the curative effects are not satisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Ciprofloxacin Lactate 5% Mequiquine 2%

[0010] The preparation process of the present invention is: take prescription amount ciprofloxacin lactate, acemequine respectively, add dimethylacetamide, dimethylformamide, polyethylene glycol, water for injection to 60% of total volume, stir Dissolve; then add 0.2% sodium bisulfite and 0.01% disodium edetate in the prescribed amount, and stir to dissolve; add water for injection to the full amount, adjust the pH value, filter, pot, sterilize at 100°C for 30 minutes, Cooling, light inspection, printing, packaging, that is.

Embodiment 2

[0012] Ciprofloxacin Hydrochloride 5% Acetyl Mequin 2%

[0013] The preparation process of the present invention is as follows: respectively take prescription amounts of ciprofloxacin hydrochloride and acemequine, add dimethylacetamide, dimethylformamide, polyethylene glycol, and water for injection to a total volume of 60%, and stir Dissolve; then add 0.2% sodium bisulfite and 0.01% disodium edetate in the prescribed amount, and stir to dissolve; add water for injection to the full amount, adjust the pH value, filter, pot, sterilize at 100°C for 30 minutes, Cooling, light inspection, printing, packaging, that is.

Embodiment 3

[0015] Ciprofloxacin Lactate 2.5% Mequiquine 1%

[0016] The preparation process of the present invention is: take prescription amount ciprofloxacin lactate, acemequine respectively, add dimethylacetamide, dimethylformamide, polyethylene glycol, water for injection to 60% of total volume, stir Dissolve; then add 0.1% sodium sulfite and 0.01% disodium edetate, stir to dissolve; add water for injection to the full amount, adjust the pH value, filter, pot, sterilize at 100°C for 30 minutes, cool, and light Inspection, printing, packaging, that is.

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PUM

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Abstract

The present invention is compound ciprofloxacin injection for animal and its preparation. The compound ciprofloxacin injection consists of main medicine components comprising ciprofloxacin lactate or ciprofloxacin hydrochloride 2.5-10 wt% and mequindox 1-4 wt%; additive comprising antioxidant 0.1-0.2 wt% and metal complexing agent 0.01-0.02 wt%; and solvent in 86-96.5 wt%. The present invention provides one new veterinary medicine for treating animal's intestinal tract diseases and has the advantages of reasonable recipe, stable preparation, high bioavailability, determined curative effect, etc.

Description

technical field [0001] The invention relates to a veterinary compound ciprofloxacin injection for treating intestinal diseases of livestock and poultry and a preparation process thereof. Background technique [0002] The compound ciprofloxacin injection made from the main drug ciprofloxacin lactate, ciprofloxacin hydrochloride and acetylmequin is effective in treating yellow scour, pullorum and clostridial enteritis (red scour) of piglets. ); lamb dysentery; calf diarrhea; livestock necrotic enteritis, dysentery, paratyphoid; chick pullorum, chicken colibacillosis, fowl typhoid and other intestinal diseases have a significant effect. Intestinal diseases of livestock and poultry are prone to onset, seriously affecting their growth, untimely treatment, high mortality, and causing huge economic losses to farmers. At present, veterinary clinical treatment of intestinal diseases of livestock and poultry is generally a single preparation, and most of the curative effects are not ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/496A61K9/20A61K47/34A61K47/16A61P31/04A61K31/47A61K47/10A61K47/18
Inventor 胡少平张克曾标其
Owner 江西百思技术咨询有限公司