Methods for treating FSH related conditions with GnRH antagonists

a technology of gnrh and fsh, which is applied in the direction of drug compositions, extracellular fluid disorders, peptide/protein ingredients, etc., can solve the problems of lh no longer being produced, histamine-releasing activity, and worsening the condition, so as to and reduce the plasma fsh and lh levels
US20070015714A1Inactive Publication Date: 2007-01-18PRAECIS PHARM INC
11 Cites 2 Cited by

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
PRAECIS PHARM INC
Publication Date
2007-01-18
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Methods for treating FSH related conditions, such as prostatic intraepithelial neoplasia, pedophilia, infertility, or vaginal bleeding, with GnRH antagonists are disclosed. The methods of the invention generally feature administering to a subject a GnRH antagonist suitable for in vivo administration and able to reduce both plasma FSH and LH levels in a subject, in an amount or in a formulation effective to reduce plasma FSH levels in the subject to a symptom alleviating level. In vitro fertilization and male contraceptive methods are also provided.
Need to check novelty before this filing date? Find Prior Art

Description

RELATED APPLICATIONS

[0001] This application is a Continuation of U.S. patent application Ser. No. 09 / 793,669 filed on Feb. 28, 2001 which, in turn, claims priority to U.S. Provisional Application No. 60 / 185,573, filed on Feb. 28, 2000; U.S. Provisional Application No. 60 / 185,574, filed on Feb. 28, 2000; U.S. Provisional Application No. 60 / 238,337, filed on Oct. 5, 2000; and U.S. Provisional Application No. 60 / 238,338, filed on Oct. 5, 2000. The entire contents of each of the foregoing applications are incorporated herein by this reference.BACKGROUND OF THE INVENTION

[0002] Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are hormones released by the pituitary gland. These hormones regulate the functioning of the gonads and the production and maturation of gametes. LH and FSH are generally released by the pituitary gland upon prior release of a triggering hormone from the hypothalamus. Luteinizing hormone-releasing hormone (LHRH; also known as gonadotropin-releasing h...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More