Enhanced efficiency of sunscreen compositions
a sunscreen composition and efficiency technology, applied in the field of compositions, can solve the problems of affecting the feel of the composition on the skin, affecting the effect of the composition, and forming polymers beyond a certain amount, so as to prevent or reduce the occurrence of erythema, prevent or reduce the occurrence of phototoxic or photoallergic reactions, and reduce the deleterious effects of ultraviolet radiation
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example 1
Sunscreen Composition
[0054]A sunscreen composition was prepared containing amine neutralizing agents and film forming polymer as follows. To a 250 ml beaker was added 3.0 g Avobenzone, 5.0 g Octisalate, 6.0 g Oxybenzone, 15.0 g Homosalate, and 1.0 g of Glycerine to a stirred solution containing 0.51 g of Dimethylstearylamine and 3.0 g of Dermacryl 79 (an acrylate copolymer containing 14% acrylic acid, available from National Starch and Chemical Co. Bridgewater, N.J.) in 66.49 g of Ethanol. The composition was stirred until all components are dissolved. Similar compositions can be heated slightly to aid in dissolution.
example 2
Evaluation of Effect of Neutralization on SPF of Sunscreen Formulations
[0055]Sunscreen compositions were prepared as described above with varying levels and types of amine neutralizing agents. All compositions in this example contained Avobenzone (3.0 g), Octyl Salicylate (5.0 g), Oxybenzone (6.0 g), Homosalate (15.0 g), glycerin (1.0 g) and Dermacryl 79 (3.0 g) plus ethanol to bring the weight to 100 g.
[0056]All SPF measurements were conducted using poly(methyl methacrylate) (PMMA) plates (Schonberg GMBH & Co KG., 22457 Hamburg-Schnelsen, Germany) as the substrate to which the sunscreen formulas were applied. Test formulations were applied to the substrates at 1 mg / cm2 and allowed to dry for 20 minutes. A PMMA plate treated with glycerin at 1 mg / cm2 served as a reference and blank. The in vitro SPF of each formula was determined using an Optometrics SPF 290S Analzyer (Optometrics LLC, Ayer, Mass.; USA) equipped with a computer-controlled X-Y sampling stage and operated according to...
example 3
Various Amines Used for SPF Boost
[0057]Sunscreens were prepared as described in example 2 and neutralized with the indicated amine to neutralize 25 percent of the carboxylic acid groups on the Dermacryl 79. Test formulations were applied to the PMMA substrate at 2 mg / cm2. The results are shown in Table 3
TABLE 3Sample #AmineSPF11Propylamine4512Butylamine5313Hexylamine8214Octylamine10215Decylamine9316Dodecylamine7617Diethylamine6318Dihexylamine8119Triethylamine5420Tributylamine2521Dimethylaminopropylcocamide6922Cocamine8323Dimethylcocamine5224Dimethylstearylamine6525Soyamine6426Dimethylsoyamine6327Dimethylerucylamine8328Dimethylbehenylamine6229PEG-15 Cocamine5630PEG-15 Soyamine6331PEG-2 Behenylamine7132Jeffamine M-10005733Jeffamine M-20703434Control no neutralizer39
Sample 34 represents the control with no neutralization. These experiments show that, although compositions containing certain of the amines do not demonstrate a substantial boost in SPF, compositions containing examples of...
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Abstract
Description
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Application Information
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