2 results about "Cholinergic Nerves" patented technology

The present invention provides the use of an Iris fruit extract in preparing a product for preventing and / or treating nerve cell damage. The present invention establishes an AD model, and after treatment with the Iris fruit extract, the activities of SOD and GSH can be significantly increased, and the increase in MDA levels can be inhibited, and the AchE content can also be inhibited. This indicates that the Iris fruit extract can effectively improve the oxidative stress response in the pathological process of AD and improve the cholinergic nerve damage of AD.

The application discloses a method for constructing a microwave radiation animal brain injury model based on a medial septum-hippocampus CA3 cholinergic nerve loop regulation, comprising the following steps: setting electromagnetic radiation conditions, and performing electromagnetic radiation treatment on test animals; comparing whether a cholinergic nerve loop between the medial septum and the hippocampus CA3 is activated before and after the electromagnetic radiation treatment; and if the cholinergic nerve loop is activated, constructing an electromagnetic radiation animal brain injury model by using the electromagnetic radiation conditions. The application can accurately construct the electromagnetic radiation animal brain injury model, and increases the possibility of elucidating the molecular mechanism of the electromagnetic radiation brain injury effect and the research and development of prevention and treatment drugs.