The invention discloses a vehicle access system and method applied to a stereo parking garage. The system comprises a stereo parking garage control system, and also comprises a central processing unit, a first license plate recognition device disposed at the position of a garage entrance gate machine, a second license plate recognition device disposed at the position of a garage exit gate machine, and a third license plate recognition device, a first face recognition device and a man-machine dialog device which are disposed at the front of each parking chamber. The central processing unit is electrically connected with the stereo parking garage control system, the first license plate recognition device, the second license plate recognition device, the third license plate recognition devices, the first face recognition devices, the man-machine dialog devices, the garage entrance gate machine and the garage exit gate machine. License plate information serves as certification of accessing the stereo parking garage, face information serves as certification of accessing vehicles, so that owners can access the vehicles in the stereo parking garage rapidly, conveniently and efficiently.