Adjustable pulsatile myocardial internal injector

Abstract

This invention relates to an adjustable pulsation myocardial infuser comprising needle cylinder, pintle, pinhead, regulating ring, and external casing. Regulating ring can endwise slip along needle cylinder, and is provided with locking screw. External casing is inserted to needle cylinder by pinhead direction to regulating ring, and pinhead can penetrate rubber joint in front of the external casing. The exposed pinhead part is the length pierce into centrum. Needle cylinder wall adopts double scale mark (volume and length), which can simultaneous control injection amount and needle insertion in acupuncture depth. The front end of the pintle piston is diving shagreen, and can reduce residual dead space. The pinhead needle cylinder is fixed through screw thread. The invention can prevent hemorrhage at pinhole and spillage of infusion, regulate effective pinhead length, thus is suitable for varisized cardiac with different myocardial thickness, effectively avoid penetrate myocardial. The invention has simple operation, and good practicability.

Description

technical field [0001] The invention belongs to the field of clinical medicine and research, and particularly relates to an adjustable pulsating intramyocardial injector for cell transplantation and implantation of various gene carriers into pulsating myocardial tissue. Background technique [0002] At present, cell transplantation technology and gene technology have been more and more widely used in the treatment of various heart diseases, such as transplanting bone marrow stem cells or autologous atrial myocytes into autologous ventricular myocytes to treat ischemic cardiomyopathy, and injecting allogeneic ventricular myocytes into Plant embryonic stem cells and embryonic cardiomyocytes to rebuild cardiac pacemaker to treat various types of bradyarrhythmia; inject various gene vectors carrying different target genes directly into the myocardium through gene technology, or inject target cells after transfection into Inside the myocardium, exploring new ways to treat heart d...

AI Technical Summary

Problems solved by technology

However, injection into the beating myocardium has its particularity, that is, the beating myocardium is in a state of continuous contraction and relaxation, and the frequency is relatively fast (60-120 times / min); the blood supply in the myocardium is rich, and after the needle is withdrawn, Very easy to bleed and cause the injection to overflow and lose; the inside of the myocardium is the heart chamber, if the injection is too deep, the injection will enter the heart chamber, leading to serious complications such as vascular embolism

And the injection (such as cell suspension) is usually relatively viscous, while the needle tip of the TB empty needle is small, and the resistance during injection is relatively high, which sometimes causes the needle to pop out and penetrate the heart cavity, and the injection overflows from the detachment, resulting in injection failure.

[0003] Obviously, disposable TB empty needles cannot meet the above special requirements

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