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Use of piperic acid ethyl ester in preparation of medicament or healthcare product for preventing and/or treating atherosclerosis

A technology of atherosclerosis and ethyl piperate, which is applied in the field of application of ethyl piperate, can solve the problem of no atherosclerosis drugs or health care products reported in the literature of ethyl piperate

Inactive Publication Date: 2007-08-08
博日吉汗格日勒图
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] So far, there has been no literature report on the application of ethyl piperonate in the preparation of atherosclerosis prevention drugs or health products

Method used

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  • Use of piperic acid ethyl ester in preparation of medicament or healthcare product for preventing and/or treating atherosclerosis
  • Use of piperic acid ethyl ester in preparation of medicament or healthcare product for preventing and/or treating atherosclerosis
  • Use of piperic acid ethyl ester in preparation of medicament or healthcare product for preventing and/or treating atherosclerosis

Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0026] The beneficial effects of the ethyl piperonate of the present invention in preventing and / or treating atherosclerosis are further illustrated below through test examples.

[0027] Prophylactic administration test and data of ethyl piperonate on rabbits with experimental arteriosclerosis:

[0028] 1. Experimental animals and materials

[0029] Experimental animals:

[0030] New Zealand rabbits, male, weighing about 2.0kg, were provided by the Department of Experimental Animal Science, Peking University Health Science Center. According to body weight and blood lipid level, they were divided into experimental group (hyperinsulinemia group) and control group. Each group was treated as follows:

[0031] Experimental group: common feed in animal room + daily protamine zinc insulin 1.2U / kg (subcutaneous injection).

[0032] Control group: normal feed in the animal room.

[0033] Test drugs and reagents:

[0034] Ethyl piperonate was prepared by the Institute of Polymer Ch...

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Abstract

The invention relates to an application of piperic acid carbethoxy in the preparation of drug or health product used to prevent and / or treat atherosclerosis. The piperic acid carbethoxy effectively prevent and / or treat the piperic acid carbethoxy, with higher effect than other drugs. And the inventive piperic acid carbethoxy can be prepared into any types, as injection, tablet, capsule, or the like.

Description

technical field [0001] The present invention relates to the application of ethyl piperate, more specifically, the present invention relates to the application of ethyl piperate in the preparation of medicines or health care products for preventing and / or treating atherosclerosis. Background technique [0002] Atherosclerosis is a common disease that seriously endangers human health. It has been found in Egyptian mummies more than 2,000 years ago. It plays an important role in the pathogenesis of heart disease, cerebrovascular disease, and peripheral vascular disease. Effects, especially heart and brain complications are one of the main causes of death in western industrialized countries. In recent years, the incidence of cardiovascular and cerebrovascular diseases in my country, especially coronary heart disease and thrombotic cerebral infarction caused by atherosclerosis, has gradually increased. Increased superoxide caused by vasoconstriction, platelet aggregation, and mo...

Claims

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Application Information

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IPC IPC(8): A61K31/357A61K9/00A61P9/12
CPCA61K31/36A61P9/00A61P9/10A61P9/12
Inventor 博日吉汗格日勒图昭日格图那日苏麻春杰
Owner 博日吉汗格日勒图