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Compound of sulfoacid flavonecosid component in chickweed and the antivirus application and the preparing method

A technology of total flavonoid glycosides and flavonoids, which is applied in the application field of broad-spectrum antiviral drugs to achieve good antiviral effect and improve the effect of making efficiency

Inactive Publication Date: 2007-09-26
朱耕新
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, no oxyglycosides or / and carbon glycosides formed from flavonoids and saturated or / and unsaturated polysaccharides with a molecular weight below 4000 have been extracted and isolated from the plants of the genus Chickweed, and there are sulfonic acids and calcium in their structures The brown-yellow composition of the total flavonoid glycosides of the salt is used as a report on the application of broad-spectrum antiviral drugs, and the polysaccharides include oligosaccharides and polysaccharides with a molecular weight below 4000

Method used

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  • Compound of sulfoacid flavonecosid component in chickweed and the antivirus application and the preparing method
  • Compound of sulfoacid flavonecosid component in chickweed and the antivirus application and the preparing method
  • Compound of sulfoacid flavonecosid component in chickweed and the antivirus application and the preparing method

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Embodiment Construction

[0028] One), the preparation method of this product comprises following two kinds:

[0029] 1. The first preparation method comprises the following steps: washing and crushing the fresh grass or dried fresh grass of chickweed or other plants of the genus Chickweed, extracting the aqueous solution, and precipitating, centrifuging or filtering the aqueous solution Finally, liquid A is obtained; the liquid A is passed through a pre-treated macroporous resin column to absorb the components of the composition, and the column is washed with water. After the macroporous resin column is heated, the column is washed with hot distilled water to clean impurities, and the collected The dark brown distilled water that flows out is then eluted from the resin column with a lower alcohol with a concentration below 59% after heating, and the brown-red or dark brown-red solution obtained from the elution is collected, and the brown-red or dark brown-red solution is After recovering the ethanol,...

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Abstract

The invention relates to a wide-spectrum antiviral natural drug, while present world is lack in high-effect safe wide-spectrum antiviral natural drug. The invention, via two the adsorptions of two different resins, extracts a compound from plant FanLu, while the compound contains oligosaccharide or / and polyose and flavonoid as brown flavonoid glycoside with sulfonic acid group formed with apione, whose molecule weight is lower than 4, 000. The inventive compound can be used to treat AIDS, hepatitis viruse, influenza virus, or the like, without toxicity, while it can be made into 10 kinds of agent and health-care products.

Description

1. Technical field: [0001] The present invention relates to sulfonic acid and its calcium salt in the structure formed by flavonoids including apigenin and oligosaccharides and polysaccharides with a molecular weight below 4000, which are extracted from chickweed or other plants of the genus Chickweed The brown-yellow composition of the total flavonoid glycosides is used as a broad-spectrum antiviral drug. [0002] The total flavonoid glycoside components include carbon glycoside structure or / and oxyglycoside structure components formed by flavonoids and saturated or / and unsaturated polysaccharides. [0003] The ratio of flavonoid glycosides formed from oligosaccharides to flavonoid glycosides formed from polysaccharides is about 7-8.5 to 3-1.5. 2. Background technology: [0004] After searching the United States "Chemical Abstracts" (Chemical Abstracts) from 1920 to Volume 134 in 2001, the chemical constituents of the reported chickweed plants are mainly flavonoids and fla...

Claims

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Application Information

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IPC IPC(8): A61K36/36A61P31/12A61P31/14A61P31/16A61P31/18A61P31/20A61P31/22A01N65/00
Inventor 朱耕新曾毅李泽琳钱裕盛
Owner 朱耕新
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