Water soluble propolis extract with bioactivity and light-colored propolis extract

Abstract

The present invention relates to a water-soluble propolis extract and alight-coloured propolis extract with biological activity, their preparation method and edible, medicinal and cosmetic composites containing said extracts. Said two extracts are propolis extracts whose purity is 100%, contain not any harmful substance and have several medical health-care effects of inhibiting pathogenic bacteria of oral cavity and resisting oxidation. Said invention also provides the concrete steps of their preparation method.

Description

Bioactive water-soluble propolis extract and light-colored propolis extract technical field The invention relates to a water-soluble propolis extract, a light-colored propolis extract and a preparation method thereof, and a new application of the extract as antibacterial and antioxidant. The extract has multiple functions such as inhibiting oral pathogenic bacteria and anti-oxidation, and belongs to the field of deep processing of natural products. The water-soluble propolis extract and light-colored propolis extract of the present invention are especially suitable for cosmetics, health products and food additives . Background technique Propolis is a resin that bees collect from tree buds, bark and other parts of plants, mixed with glandular secretions such as bee tongue glands and wax glands, and processed and transformed by bees into a gelatinous substance. According to literature reports, propolis has a wide range of pharmacological effects, including anti-tumor, anti-...

AI Technical Summary

Problems solved by technology

At present, the extraction of propolis at home and abroad basically obtains active ingredients through extraction of high-concentration alcohol (above 75%). To a large extent

Alcohol-extracted propolis liquid has a strong smell and strong irritation, which is difficult for most consumers to accept. People who are allergic to alcohol are also prone to allergic reactions when using it, which increases allergens. It is very restrictive as a raw material for cosmetics and oral health products; solid Alcohol-extracted propolis is not highly irritating, but it is not easily soluble in water. The dosage form of the product is limited, and some water-soluble active ingredients have not been extracted. Moreover, its biological activity and human absorption rate are not as ideal as water-extracted propolis.

Other extraction methods that have been reported generally include propolis chloroform, ethyl acetate, dichloromethane, glycerin leaching, oil extraction and supercritical extraction, etc., the cost is high, the extraction of active ingredients is incomplete, and the problem of water solubility of propolis cannot be solved. question

Invention patent 97111643 makes water-soluble propolis by alkaline treatment of alcohol-extracted propolis, but the alkaline environment has a certain interference effect on the activity of propolis, and the biological effect is affected to a certain extent

Since propolis is a dark brown lumpy solid, and the high-concentration ethanol propolis extract is also brown powder or dark brown solid, adding a very small amount of propolis to cosmetics is not enough to exert the biological activity of propolis, and the addition of an effective dose makes the product The color of propolis is brown, which is not satisfactory; and the water insolubility of propolis makes it difficult to disperse evenly in cosmetics. Although ethanol can be used as a solvent to dissolve propolis well, the use of ethanol has great damage to the skin. The above defects have greatly restricted the application of propolis in cosmetics

At present, there are no reports of light-colored propolis at home and abroad. Light-colored propolis is an innovation in the research of deep processing of propolis products.

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