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Method for preparing preparation for treating gastroenteritis and its new use

A technology for enteritis and pharmaceutical preparations is applied in the field of preparation of preparations for treating gastroenteritis, and can solve the problems of complicated production procedures, large dosage, and many chances of suffering from adverse reactions.

Active Publication Date: 2008-02-20
JIANGXI HERBI SKY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In the patent with the application number 200610018336.6, because some of the fenugreek and Dijincao are used for crushing and used as medicine, in addition to the disadvantages of many adverse reactions and large doses, there are also disadvantages such as complicated production processes, long working hours, and relatively high costs. place

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Dijin grass 970g, yellow hair ear grass 1300g, camphor root 970g, fenugreek 510g, maple leaves 510g

[0021] Grind the fenugreek into a coarse powder, moisten it with water for 0.5 hours, add 10 times the amount of water to distill twice, 2 hours each time, collect the volatile oil, and store the distillate in another device for later use; Add water to decoct camphor tree roots and maple leaves twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate until the relative density measured at 80°C is 1.30, dry under reduced pressure, pulverize, add microcrystalline cellulose, and distill The liquid is moistened and granulated, and dried; another 3 g of camphor is taken, dissolved in absolute ethanol, sprayed into the granules together with the volatile oil of fenugreek, granulated, packed into capsules, and made into 1000 granules, and the product is ready.

[0022] The Changyanning capsule prepared by the invention can be used for treating ...

Embodiment 2

[0024] Dijin grass 1100g Yellow hairy ear grass 1500g Camphor tree root 1100g Cranberry 320g Maple leaves 320g

[0025] Take the fenugreek and chop it up, moisten it with water for 1 hour, add 10 times the amount of water and reflux for 4 hours, collect the volatile oil, and set aside; add the dregs and decoction of Dijin grass, yellow hair ear grass, camphor tree root, and maple leaves to decoct twice. The second time is 2 hours, the second time is 1.5 hours, the decoction is combined, filtered, the filtrate is concentrated to a relative density of 1.30 when measured at 80 ° C, starch is added, granulated, dried, and another 2.5ml of camphor oil is taken and diluted with absolute ethanol , sprayed into the granules together with the volatile oil of fenugreek, granulated, and pressed into 1000 pieces, that is to say.

[0026] The Changyanning preparation of the invention can be used for indigestion and constipation in children.

Embodiment 3

[0028] Dijin grass 990g, yellow hair ear grass 1500g, camphor root 990g, fenugreek 330g, maple leaves 330g

[0029] Grind the fenugreek into a coarse powder, put it into an extraction tank, extract at 15MPa, temperature 45°C, carbon dioxide as the extraction agent, and extract at a flow rate of 25kg / h for 90min, collect the volatile oil, and set aside; Add water to decoct camphor tree roots and maple leaves twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.30 at 80°C, add sucrose powder, granulate, and dry; take another 2 g of camphor, Dissolve it with absolute ethanol, add it to the volatile oil of fenugreek, spray it into granules, adjust the granules, and make granules.

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PUM

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Abstract

The present invention discloses a preparation method and a new usage of a pharmaceutical preparation for treating enteritis. The preparation method is that: the Chinese mosla herb is distilled by using water vapor or is extracted the volatile oil by refluxing / supercritical extraction, the distilled liquid is preserved in another container for standby; the medicine residues, humifuse euphorbia herb, goldhair hedyotis herb, camphor root and maple leaves are treated by water extraction for 2 to 3 times, 1 to 4 hours for each time, the water extraction liquid is concentrated to the relative density of 1.04 to 1.35 at 80 DEG C, the excipients are added, then drying and smashing are carried out, the distilled liquid of Chinese mosla herb is used for granulation or the clear paste is dried at low temperature to prepare the dry extract, then the smashing is carried out, the excipients are added, the distilled liquid is used for granulation and drying, the volatile oil of the Chinese mosla herb and the camphor or camphor oil which is dissolved and diluted by ethanol are sprayed in, so as to prepare the granules by granulation or prepare the tablets by compression / prepare the capsules. The present invention also discloses the new usage of the preparation for treating enteritis prepared by the method in the treatment of constipation.

Description

technical field [0001] The invention relates to the field of Chinese herbal medicines, in particular to a preparation method and a new application of a preparation for treating gastroenteritis. Background technique [0002] The difference between the present invention and the patent application No. 200610018336.6 "a pharmaceutical composition for treating acute and chronic gastroenteritis and its preparation method" filed by the inventor on February 11, 2006 is: 1. In the invention, part of the Herba chinensis and Cynorrhizae in the original process were crushed, and the remaining part was extracted by water, and the volatile oil was first extracted from Cynorrhizae, and then the dregs were extracted by water with other medicinal materials to make an extract, and no crude drug powder was used as medicine. In this way, the quality of the product can be easily controlled, and the dosage and impurities can be reduced to avoid adverse reactions; two, the present invention also h...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61K9/16A61K9/48A61K9/20A61P1/04A61P1/10A61P1/12A61K31/125
Inventor 徐发红陈科茂艾样开张传亮徐昌海
Owner JIANGXI HERBI SKY CO LTD
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