Progesterone injection and method for preparing the same

A progesterone and injection technology, applied in the field of progesterone injection and its preparation, can solve the problems of inability to solve the problem of progesterone solubility, the sterilization time cannot be longer than 15 minutes, the sterilization temperature cannot be higher than 105°C, and the like, To achieve the effect of reducing local injection irritation and allergic side effects, reducing hemolysis and histamine release, and improving drug efficacy and safety
CN101152186AInactive Publication Date: 2008-04-02曲靖平和安康医药保健有限公司
0 Cites 42 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
曲靖平和安康医药保健有限公司
Publication Date
2008-04-02
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention provides a progesterone injection and the preparation method, which solves the problems of strong pungency, inconvenient use with prior progesterone injection, the problems of low stability and poor quality with prior progesterone micoremulsion, and the problems of high cost with asepsis preparation process. The weight percentage of the progesterone injection is: 0.5 to 2 percent of progesterone, 15 to 35 percent of oil for injection, 1 to 12 percent of emulsifier, 0.1 to 1 percent of assistant emulsifier, 0.2 to 2 percent of stabilizer, 0.01 to 2.5 percent of zntioxidant and allowance of water.
Need to check novelty before this filing date? Find Prior Art

Description

Technical field:

[0001] The invention relates to a progesterone injection and a preparation method thereof. Background technique:

[0002] Progesterone is a natural progestin, insoluble in water, soluble in organic solvents such as ethanol. Progesterone is a commonly used sex hormone drug, which can regulate hormone balance. Progesterone has the general effect of progesterone. It is widely used in clinical practice, mainly for menstrual disorders, such as amenorrhea and functional uterine bleeding, luteal phase insufficiency, aura Treatment of miscarriage and recurrent miscarriage, premenstrual tension syndrome, and estrogen cycles against the effects of pure estrogen on the endometrium.

[0003] Progesterone (Progesterone / Progetin) is a fat-soluble substance that is insoluble in water. It absorbs a small amount after oral administration and is quickly metabolized and inactivated by the liver. Therefore, only oil solution injections can be used clinically. When the injecti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More