Chinese traditional medicine compound, method for preparing the same and use thereof

A compound and traditional Chinese medicine technology, applied in pharmaceutical formulations, drug combinations, anti-tumor drugs, etc., can solve the problems of high radiotherapy costs, increased toxic and side effects, and increased therapeutic effects, and achieves inhibition of recurrence and metastasis. Widespread effect on cancer

Inactive Publication Date: 2008-05-07
南京宇道科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the best-selling chemical drugs for tumors include paclitaxel, gemcitabine, topotecan, docetaxel, etc. Although these drugs have good therapeutic effects, they also have many toxic and side effects, such as bone marrow suppression, leukocyte Feeling low, diarrhea, nausea, tiredness, etc.
Many chemical drugs are often used in combination in the treatment of tumors. While increasing the therapeutic effect, the toxic and side effects are also greatly increased. In addition, various factors such as the high cost of tumor chemotherapy and radiotherapy, and poor tolerance of patients make the treatment It cannot be carried out smoothly, and a considerable number of people give up treatment due to intolerance or economic reasons

Method used

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  • Chinese traditional medicine compound, method for preparing the same and use thereof
  • Chinese traditional medicine compound, method for preparing the same and use thereof
  • Chinese traditional medicine compound, method for preparing the same and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1 tablet

[0025] Evodia 10kg Guanguan Vine 3kg

[0026] Baiying 10kg Snakevine 3kg

[0027] Spathiphyllum 3kg Spathiphyllum 3kg

[0028] Honeysuckle Vine 3kg Wild Grape Vine 3kg

[0029] Big blood vine 3kg Sophora flavescens 3kg

[0030] Chong Lou 1kg Licorice 3kg

[0031] Add 10 times 80% ethanol solution to the used weight of Chinese medicinal materials Evodia rutaecarpa and Baiying coarse powder, reflux extraction 3 times, the extraction time is 2.5 hours, 1.5 hours, 1 hour respectively, filter, combine the extracts, concentrate and dry , dregs for later use; mix the dregs of the above two medicinal materials with other ten medicinal materials, add 8 times the amount of water to decoct 3 times, the decoction time is 2 hours, 1.5 hours and 1 hour respectively, combine the decoction liquid, concentrate When the relative density is 1.30 (25°C), add ethanol solution to make the alcohol concentration reach 70%. After stirring well, let stand overnight, filte...

Embodiment 2

[0037] Embodiment 2 hard capsules

[0038] Evodia 20kg Guanguan Vine 6kg

[0039] Baiying 20kg Snakevine 6kg

[0040] Millipede vine 6kg Millipede 6kg

[0041] Honeysuckle vine 6kg Wild grape vine 6kg

[0042] Big blood vine 6kg Sophora flavescens 6kg

[0043] Chong Lou 3kg Licorice 6kg

[0044] Add 8 times of 70% ethanol solution to the used weight of Chinese medicinal materials Evodia rutaecarpa and Baiying coarse powder, reflux and extract 3 times, the extraction time is 3 hours, 2 hours, 0.5 hours respectively, filter, combine the extracts, concentrate and dry , dregs for later use; mix the dregs of the above two medicinal materials with other ten medicinal materials, add 10 times the amount of water to decoct 3 times, the decoction time is 3 hours, 2 hours, 1 hour respectively, combine the decoction liquid, concentrate When the relative density is 1.10 (25°C), add ethanol solution to make the alcohol concentration reach 80%, stir well, let it stand overnight, filter,...

Embodiment 3

[0049] Embodiment 3 pills

[0050] Evodia 1kg Evodia 1kg

[0051] Baiying 1kg Snakevine 1kg

[0052] Spathiphyllum 1kg Spathiphyllum 1kg

[0053] Honeysuckle vine 1kg Wild grape vine 1kg

[0054] Sagittarius 1kg Sophora flavescens 1kg

[0055] Chonglou 0.5kg Licorice 1kg

[0056] Add 5 times of 60% ethanol solution to the used Chinese medicinal materials Evodia rutaecarpa and Baiying coarse powder, warm soak and extract 3 times, the extraction time is 6 hours, 4 hours and 2 hours respectively, filter, combine the extracts and concentrate, Dry the medicinal residues for later use; mix the medicinal residues of the above two medicinal materials with the other ten medicinal materials, add 5 times the amount of water and decoct 3 times, the decoction time is 2 hours, 1 hour and 0.5 hours respectively, and the decoction liquid is combined. Concentrate to a relative density of 1.05 (25°C), add ethanol solution to make the alcohol concentration more than 50%, stir well, let it s...

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PUM

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Abstract

The invention provides a Chinese traditional medicine compound prescription, and a preparation method and the purpose thereof, which mainly provides the Chinese traditional medicine compound prescription consisting of evodia, marsdenia tenacissima, climbing nightshade, oriental biter weed, Chinese fevervine, spatholobus stem, honey-suckle stem, wild grapevine, sargentg loryvine, Radix sophora flavescens, Paris Rhizome, licorice, etc. The preparation method comprisesthe following steps: step one, the alcohol reflux or the warm immersion abstraction of the evodia and the climbing nightshade, step two, the water extract-ethanol precipitation of gruffs and the rest medicinal materials, and step three, the blending of aqueous extract and ethanol extract. The invention provides the purposes of the compound prescription and the extract for the medicines of curing lung cancer, liver cancer, stomach cancer, rectal cancer, oophoroma, cervical carcinoma, prostatic cancer, bone cancer and other cancers, and simultaneously the invention also provides all administration forms including oral administration, rectum administration, intramuscular administration, vena administration, nasal cavity administration, vagina administration, subcutaneous administration, etc., and all preparation forms accepted by pellet, hard capsule, soft capsule, granula, oral liquid, syrup and pharmacy.

Description

Technical field: [0001] The invention belongs to the field of research and development of traditional Chinese medicines, and relates to a compound Chinese medicine and its preparation method and application, in particular to a Chinese herbal medicine composed of Evodia rutaecarpa, Tongguanteng, Baiying, Snakevine, Caulis teng, Spatholobus, Lonicerae vine, wild grapevine, Chinese medicine compound composed of Sacred Radix Sinensis, Sophora Sophora, Chonglou, Licorice and other Chinese medicinal materials and its preparation method, also relates to the preparation of the compound and its preparations in the treatment of lung cancer, liver cancer, gastric cancer, rectal cancer, ovarian cancer, cervical cancer, prostate cancer, etc. Cancer, bone cancer and other cancer diseases, especially the application of drugs for the treatment of various primary bronchial lung cancers such as lung adenocarcinoma, small cell lung cancer, lung squamous cell carcinoma, and large cell lung cancer....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P35/00
Inventor 阮锦满史美耿王永毅石海云姚小燕钱世祥朱静娟
Owner 南京宇道科技开发有限公司
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