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Technique for preparing fufang danshen pian

A compound Danshen tablet and a preparation process technology are applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve problems such as inability to extract, and achieve the effects of improving utilization rate, reducing environmental pollution, and shortening production cycle

Inactive Publication Date: 2008-05-21
HENAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of the above process is that the effective ingredients contained in the salvia miltiorrhiza, tanshinone IIA and salvianolic acid B, cannot be effectively extracted.

Method used

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  • Technique for preparing fufang danshen pian
  • Technique for preparing fufang danshen pian
  • Technique for preparing fufang danshen pian

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: In step (1), the weight ratio of salvia miltiorrhiza to ethanol is 1:5, extract for 5 minutes, and recover the ethanol under reduced pressure until there is no alcohol smell; in step (2), the weight ratio of residue to water is 1:5, extract to a relative Density 1.02 (60°C). Other same as above.

Embodiment 2

[0027] Example 2: In step (1), the weight ratio of salvia miltiorrhiza to ethanol is 1:20, extract for 15 minutes, and recover ethanol under reduced pressure until there is no alcohol smell; in step (2), the weight ratio of residue to water is 1:20, extract to The relative density is 1.07 (60°C). Other same as above.

Embodiment 3

[0028] Example 3: In step (1), the weight ratio of salvia miltiorrhiza to ethanol is 1:30, extract for 20 minutes, and reclaim ethanol under reduced pressure until there is no alcohol smell; in step (2), the weight ratio of residue to water is 1:30, extract to a relative Density 1.12 (60°C). Other same as above.

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PUM

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Abstract

The invention relates to a new preparation technology of compound salvia tablets, comprising the steps that: (1) the salvia is taken and is put in a flash extractor together with ethanol, extracted for 5 to 20 minutes, and then centrifugated, filtered, the filtered liquid is decompressed to recycle the ethanol for spare; (2) the residue as well as water are put into the flash extractor and extracted for 5 to 20 minutes, centrifugated, and the extracted liquid is concentrated to clear plaster with a relative density of 1.02 to 1.12 (60 DEG C), the salvia fine powder is obtained by spraying and drying; (3) the super micro-powder of notoginseng is obtained by the super-micro pulverization of the notoginseng; (4) grains are made by the filtered liquid after the ethanol is recycled in the step (1), the salvia fine powder in the step (2) and the super micro-powder of the notoginseng in the step (3) as well as supplementary materials and dried, the borneol is ground finely and evenly mixed with the grains, pressed into pill and packed. The salvia extraction procedure provided by the invention adopts a historrhexis technology without heating, the active ingredient content in the obtained salvia tablets is remarkably increased; the notoginseng is finely crushed into super-micro powder in order to favor the absorption of the active ingredient. The treatment effect is great and the energy consumption is low.

Description

technical field [0001] The invention relates to a new preparation process of compound salvia miltiorrhiza tablets. Background technique [0002] Compound Danshen Tablets is a variety recorded in the Chinese Pharmacopoeia in previous editions. It is refined from three herbs of Danshen, Panax notoginseng and Borneol. It has the effects of promoting blood circulation, removing blood stasis, regulating qi and relieving pain. For chest obstruction caused by qi stagnation and blood stasis, symptoms: chest tightness, tingling pain in the chest area; coronary heart disease angina pectoris, see the above syndromes. It is a commonly used Chinese patent medicine in clinical practice. [0003] The current version of the Chinese Pharmacopoeia process is as follows: (1) the above three flavors, dandelion is added to ethanol and heated to reflux for 1.5 hours, the extract is filtered, the filtrate is recovered from ethanol and concentrated to an appropriate amount, and set aside; the dreg...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K9/20A61P9/10A61K31/045
Inventor 李钦张昀马凤仙
Owner HENAN UNIVERSITY
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