Antiphlogistic antiviral medicinal composition, and its preparation method and application

A composition and antiviral technology, applied in the field of medicine, can solve the problems of large dosage, large side effects, complicated process, etc., and achieve the effects of huge social benefits, improved pharmacological effects, and easy industrialization.

Active Publication Date: 2008-05-28
HEBEI IDEAL & HIGHTECH PHARMA
View PDF4 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, the Chinese invention patent publication 200410064367.6 of Chengdu Sanming Pharmaceutical Research Institute, the title of the invention is "a pharmaceutical composition for treating acute and chronic pharyngitis and its preparation method", which discloses a pharmaceutical composition for treating acute and chronic pharyngitis, The composition is made of various medicinal materials such as traditional Chinese medicine Shegan, Scutellaria baicalensis, Platycodon grandiflorum, etc., and has complex medicinal properties, and the composition needs to extract the ingredients of the traditional Chinese medicine during preparation, the process is complicated, and the composition proposed in the extraction process Unclear, large dosage during treatment, large side effects
This is because traditional Chinese medicine has many ingredients and its medicinal properties are complex, and some components that are proposed to be extracted that actually have no pharmacological effects may show some side effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Antiphlogistic antiviral medicinal composition, and its preparation method and application
  • Antiphlogistic antiviral medicinal composition, and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0091] Example 1 Preparation of Shegan Total Flavonoids

[0092] Take 10 kg of dried herbal medicine, extract three times with 10 times the amount of 70% ethanol, 2 hours each time, collect the extract, recover the ethanol and add water to 100L, place it at room temperature, centrifuge, and pass the supernatant through AB-8 macroporous adsorption resin, first Elute with water until colorless, remove impurities soluble in polar solvents, discard, then use 4BV (resin bed volume) 70% ethanol for elution, collect the ethanol eluate, and reduce the eluate after reclaiming ethanol Press and dry to obtain the total flavonoids. The quality of the extract is 600g, it is a light brown powder, and the content of total flavonoids is 65% as detected by a UV-spectrophotometer. The PHLC spectrum of the extract is shown in FIG. 1 .

Embodiment 2

[0093] Example 2 Preparation of powder injection form

[0094] Take 8 g of total flavonoids of Scutellaria baicalensis prepared in the above example 1, 2 g of total flavonoids of Scutellaria baicalensis and 5 g of mannitol, dissolve them together in 500 ml of water for injection, and adopt the existing preparation process of powder injection to prepare 1 part of total flavonoids of Scutellaria baicalensis and 4 parts of total flavonoids of Scutellaria baicalensis and 4 parts of total scutellaria baicalensis. A pharmaceutical composition in powder injection form of flavonoids.

[0095] The Scutellaria baicalensis extract described therein is purchased from the market and produced by Xi'an Zhongxin Biotechnology Co., Ltd., wherein the content of baicalin is higher than 85%.

Embodiment 3

[0096] Example 3 Preparation of capsules

[0097] Using the Scutellaria baicalensis extract and Shegan extract used in Example 2, take 6g of Scutellaria baicalensis extract, 14g of Shegan extract and 40g of starch, mix them uniformly, granulate with 85% ethanol, dry at 60°C, granulate, pack into capsules, and prepare A pharmaceutical composition in capsule dosage form containing 3 parts of Scutellaria baicalensis extract and 7 parts of Shegan extract was obtained.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
Login to view more

Abstract

The invention discloses an antibacterial and antiviral drug combination, containing scutellaria total flavone and blackberry lily total flavone as active components and a routine pharmaceutical carrier. The combination has the characteristics that distinct antibacterial and antiviral functions are possessed; the healing efficacy is better than that of using scutellaria root total flavone or blackberry lily total flavone singularly; the compound combination of the effective position of traditional Chinese medicine of with better healing efficacy and convenience and the preparation thereof are supplied for clinical use; not only the pharmacological and clinical healing effect of traditional Chinese medicine is improved, but inclusion content also is reduced; diverse preparations such as peroral typed, injection typed, or external typed preparation can be made, wherein the peroral preparation is preferred. The invention has the advantages that the drug combination and the preparation thereof can be applied to the treatment of diseases such as respiratory tract infection, acute bacillary dysentery, virus hepatitis, and oral ulcer, etc.; the purposes of safety, effectiveness, stability, controllability, and convenience of a modern Chinese herbal compound are realized.

Description

technical field [0001] The present invention relates to the field of medicine, and more specifically, the present invention relates to an anti-inflammatory and anti-viral pharmaceutical composition, which uses total flavonoids of Scutellaria baicalensis and total flavonoids of Radix Scutellariae as active ingredients. The composition has the function of anti-inflammation and anti-virus, and has good therapeutic effects on diseases caused by bacterial and / or viral infections, especially upper respiratory tract infection and viral pneumonia. Background technique [0002] Virus infection, especially the ravages of SARS and bird flu in recent years, has become a serious topic that people pay attention to in modern society. Statistics show that about 60% of epidemic infectious diseases are caused by virus infection. The research and development of antiviral drugs has naturally become a hot spot for investment in the pharmaceutical industry. So far, more than 3,000 viruses have ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K9/16A61K9/20A61P31/04A61P31/12A61P11/00
CPCY02A50/30
Inventor 夏彤魏兵黄国胜胡竹梅王海强
Owner HEBEI IDEAL & HIGHTECH PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap