Veterinary compound clove linimentum for eperythrozoonosis and preparing method thereof

A technology of eperythrozoonosis and clove, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problem of reducing the infection intensity of eperythrozoon, which cannot completely solve the problem, and cannot be purified Attached to red bodies and other problems, to achieve the effect of reduced infection intensity, reliable effect, and stable storage

Inactive Publication Date: 2008-07-30
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] After searching the literature of the prior art, it was found that Huang Shuihong et al. published "Exploration of Drug Efficacy of Porcine Eperythrozoonosis" in the 2nd issue of "Contemporary Animal Husbandry" in 2004. Jing, sulfamethoxine sodium, oxytetracycline, chlortetracycline, metronidazole and doxycycline in the treatment of Eperythrozoon disease can all reduce the infection intensity of Eperythrozoon, but none of them can purify Eperythrozoon in the blood. body, can not completely solve the problem

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Veterinary compound clove liniment for Eperythrozoonosis is made by the following method:

[0040] (1) Take by weight clove oil 10g, artemether 10g, levamisole hydrochloride 5g, propylene glycol 25g, isopropanol 30g, azone 5g, glycerin 6g;

[0041] (2) Azone is dissolved in propylene glycol and Virahol;

[0042] (3) clove oil is dissolved in the solution that (2) obtains;

[0043] (4) Artemether is dissolved in glycerin;

[0044] (5) levamisole hydrochloride is dissolved in water;

[0045] (6) Mix (3), (4) and (5) obtained solutions uniformly, then filter;

[0046] (7) Add water to the filtrate to make up 100ml, mix well, and then make compound clove liniment for animals.

Embodiment 2

[0048] Veterinary compound clove liniment for Eperythrozoonosis is made by the following method:

[0049] (1) Take by weight clove oil 20g, artemether 15g, levamisole hydrochloride 15g, propylene glycol 14g, isopropanol 20g, azone 3g, glycerin 3g;

[0050] (2) Azone is dissolved in propylene glycol and Virahol;

[0051] (3) clove oil is dissolved in the solution that (2) obtains;

[0052] (4) Artemether is dissolved in glycerin;

[0053] (5) levamisole hydrochloride is dissolved in water;

[0054] (6) Mix (3), (4) and (5) obtained solutions uniformly, then filter;

[0055] (7) Add water to the filtrate to make up 100ml, mix well, and then make compound clove liniment for animals.

Embodiment 3

[0057] Veterinary compound clove liniment for Eperythrozoonosis is made by the following method:

[0058] (1) Take by weight clove oil 15g, artemether 12g, levamisole hydrochloride 10g, propylene glycol 20g, isopropanol 30g, azone 2g, glycerol 6g;

[0059] (2) Azone is dissolved in propylene glycol and Virahol;

[0060] (3) clove oil is dissolved in the solution that (2) obtains;

[0061] (4) Artemether is dissolved in glycerin;

[0062] (5) levamisole hydrochloride is dissolved in water;

[0063] (6) Mix (3), (4) and (5) obtained solutions uniformly, then filter;

[0064] (7) Add water to the filtrate to make up 100ml, mix well, and then make compound clove liniment for animals.

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Abstract

The invention relates to a veterinary compound clove liniment treating eperythrozoonosis in the biotechnology field and a preparation method thereof. The invention is mainly prepared by main materials, such as clove oils, artemethe and levamisole hydrochloride, served with auxiliary materials, such as propanediol, isopropanol, laurocapram and glycerol, and the main materials and the auxiliary materials are treated by conventional methods, such as weighing, stirring, well mixing, measuring and packaging, etc. The compound preparation can be applied to skins and the weight percentage of raw materials is clove oils of 10 to 20 percent, the artemether of 10 to 15 percent, the levamisole hydrochloride of 5 to 15 percent, the propanediol of 10 to 30 percent, the isopropanol of 20 to 30 percent, the laurocapram of 1 to 5 percent and the glycerol of 2 to 6 percent. The invention has the advantages of a low cost, storage stability, reliable effect and convenient medication, etc., so the invention is a novel and highly-efficient preparation for treating eperythrozoonosis of animals.

Description

technical field [0001] The invention relates to a preparation in the field of biotechnology and a preparation method thereof, in particular to a veterinary compound clove liniment for eperythrozoonosis and a preparation method thereof. Background technique [0002] Eperythrozoonosis is a zoonotic disease caused by Eperythrozoon parasitizing on the surface of human and animal red blood cells, plasma and bone marrow. Bring great harm to human health and aquaculture. However, there is no safe, efficient and environmentally friendly specific drug for the clinical treatment of the disease at present. Some drugs are commonly used in clinical practice and have good effects, but because they are used alone, drug resistance is prone to occur, such as the instability of oxytetracycline preparations commonly used in clinical practice, and the side effects of Bernier are relatively large, so they are safe and efficient. The invention of convenient compound medicine has important clini...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61K47/22A61P31/00A61K31/429A61K31/357
Inventor 华国修李政萍崔立沈权陈丕仁
Owner SHANGHAI JIAO TONG UNIV
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