Imidocarb dipropionate compound preparations for eperythrozoonosis for animals and preparation
A technology of imidazolium dipropionate and eperythrozoonosis, which is applied in the field of preparations and its preparation, and can solve problems such as inability to purify eperythrozoonosis and inability to completely eliminate eperythrozoonosis
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Embodiment 1
[0024] The veterinary compound preparation containing imidazolium dipropionate is prepared by the following method:
[0025] (1) Weigh 15g of imidazolium dipropionate, 5g of astragalus extract, 12g of florfenicol, 15g of artesunate, 33g of β-cyclodextrin, and 20g of Fumei powder;
[0026] (2) mix artesunate and β-cyclodextrin;
[0027] (3) add imidazolium dipropionate and florfenicol, and mix;
[0028] (4) mix astragalus extract and Fumei powder;
[0029] (5) Mix the solutions obtained in the above step (3) and step (4), and mix evenly to prepare a compound preparation containing imidazolium dipropionate.
[0030] The compound preparation containing imidazuron dipropionate prepared above is used to treat rats artificially infected with Eperythrozoon. Rats were randomly divided into 5 groups, namely: blank control (1), imidazolium dipropionate (2), Bernier (3), long-acting oxytetracycline (4), compound imidazolium dipropionate (5 ). The experimental results are shown in Ta...
Embodiment 2
[0038] The veterinary compound preparation containing imidazolium dipropionate is prepared by the following method:
[0039] (1) Weigh 5 g of imidazolium dipropionate, 2 g of astragalus extract, 3 g of florfenicol, 5 g of artesunate, 65 g of β-cyclodextrin, and 20 g of Fumei powder;
[0040] (2) mix artesunate and β-cyclodextrin;
[0041] (3) add imidazolium dipropionate and florfenicol, and mix;
[0042] (4) mix astragalus extract and Fumei powder;
[0043] (5) Mix the solutions obtained in the above step (3) and step (4), and mix evenly to prepare a compound preparation containing imidazolium dipropionate.
[0044] The compound preparation containing imidazolium dipropionate prepared above was used for anti-eperythrozoon drug susceptibility test in vitro. The implementation is as follows: aseptically collect anticoagulant blood, add 1:7 nutrient solution RPMI-1640, add the prepared drug mother solution to each well, shake gently, and then place the 96-well plate in a 37°C...
Embodiment 3
[0063] The veterinary compound preparation containing imidazolium dipropionate is prepared by the following method:
[0064](1) Weigh 8 g of imidazolium dipropionate, 4 g of astragalus extract, 6 g of florfenicol, 6 g of artesunate, 50 g of β-cyclodextrin, and 26 g of Fumei powder;
[0065] (2) mix artesunate and β-cyclodextrin;
[0066] (3) add imidazolium dipropionate and florfenicol, and mix;
[0067] (4) mix astragalus extract and Fumei powder;
[0068] (5) Mix the solutions obtained in the above step (3) and step (4), and mix evenly to prepare a compound preparation containing imidazolium dipropionate.
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