Application of myricetin in medicament for treating prostate gland disease

A technology for prostatitis and prostatic hyperplasia, applied in the field of traditional Chinese medicine, can solve problems such as unfavorable long-term use, unsatisfactory effect, and long-term medication

Inactive Publication Date: 2008-09-24
吉林天药现代中药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of prostatitis and benign prostatic hyperplasia is mainly based on western medicine or traditional Chinese medicine compound preparations, and the effect is not ideal, and the treatment of this disease requires long-term medication, and the side effects of chemical drugs are large, which is not beneficial for long-term use

Method used

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  • Application of myricetin in medicament for treating prostate gland disease
  • Application of myricetin in medicament for treating prostate gland disease
  • Application of myricetin in medicament for treating prostate gland disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1 (capsule)

[0043] Prescription: Myricetin: 150g

[0044] Starch 30g

[0045] Sodium carboxymethyl starch 20g

[0046] Appropriate amount of 3% hydroxypropyl methylcellulose aqueous solution

[0047] Mix myricetin raw material, starch and sodium carboxymethyl starch evenly, granulate with 3% hydroxypropylmethylcellulose aqueous solution, dry, granulate, pack into No. 1 capsules, and make 1000 capsules. Each capsule contains myricetin 150mg. 2 capsules each time. 3 times a day.

Embodiment 2

[0048] Embodiment 2 (tablet)

[0049] Prescription: Myricetin: 150g

[0050] Lactose 30g

[0051] Sodium carboxymethyl starch 20g

[0052] Appropriate amount of 3% hydroxypropyl methylcellulose aqueous solution

[0053] Talc powder 2.5g

[0054] Myricetin raw materials, microcrystalline cellulose, sodium carboxymethyl starch, mixed evenly, granulated with 3% hydroxypropyl methylcellulose aqueous solution, dried, granulated, added talcum powder, mixed evenly, compressed into tablets, made into 1000 tablets, Instantly. Each tablet contains myricetin 150mg. 2 tablets each time. 3 times a day.

Embodiment 3

[0055] Embodiment 3 (sustained-release capsules)

[0056] Prescription: Myricetin: 150g

[0057] Microcrystalline cellulose 30g

[0058] Hypromellose K4M 20g

[0059] Appropriate amount of 3% hydroxypropyl methylcellulose aqueous solution

[0060] Myricetin raw materials, microcrystalline cellulose, and hypromellose K4M are mixed evenly, granulated with 3% hydroxypropyl methylcellulose aqueous solution, dried, granulated, packed into No. 1 capsules, and made into 1000 capsules. . Each capsule contains myricetin 150mg. 2 capsules each time. 3 times a day.

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Abstract

The invention discloses the application of myricetin in the treatment of prostatic hyperplasia and/or prostatitis diseases. The prepared drug can contain only myricetin or the compound of myricetin. The prepared drug can be prepared into common tablets or capsules, slow-release tablets or capsules as well as injections and suspensions.

Description

technical field [0001] The invention relates to a new therapeutic use of myricetin extracted from traditional Chinese medicine, that is, the application of myricetin in treating diseases such as benign prostatic hyperplasia and / or prostatitis and its pharmaceutical preparation, belonging to the field of traditional Chinese medicine. Background technique [0002] Myricetin (myricetin) is a kind of flavonoids, the pharmacological action that has been reported is to inhibit platelet aggregation, myricetin has inhibitory effect on rabbit platelet aggregation induced by collagen, arachidonic acid and PAF, has anti-PAF effect, is a kind of New PAF receptor antagonists. Anti-thrombotic, anti-myocardial ischemia, improving microcirculation, lowering blood sugar, anti-oxidation, protecting liver and liver, resolving light alcohol poisoning, anti-tumor, anti-inflammation, anti-mutation, preventing dental caries, eliminating free radicals in the body and other pharmacological activitie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P13/08
Inventor 赵全成南敏伦赫玉芳
Owner 吉林天药现代中药科技有限公司
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