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Chinese medicinal composition with functions of reducing fever, purging the intense heat and detoxicating and preparation method thereof and quality control method

A quality control method and detoxification technology, applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., to achieve effective quality control, stable pharmacological effects, and good identification specificity

Active Publication Date: 2008-10-01
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002]In recent years, with the improvement of people's living standards and the increase of work pressure, chronic pharyngitis, tonsillitis, etc. have become ill The disease incidence rate of symptoms is constantly increasing, and all the traditional Chinese medicines in the prior art cannot solve all the above-mentioned existing conditions, so it is urgent to find a medicine that can solve all the above-mentioned existing symptoms

Method used

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  • Chinese medicinal composition with functions of reducing fever, purging the intense heat and detoxicating and preparation method thereof and quality control method
  • Chinese medicinal composition with functions of reducing fever, purging the intense heat and detoxicating and preparation method thereof and quality control method
  • Chinese medicinal composition with functions of reducing fever, purging the intense heat and detoxicating and preparation method thereof and quality control method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0140] Embodiment 1: Granules

[0141] Coptidis 140g Rhubarb 650g Scutellaria baicalensis 200g Danpi 130g Phellodendron 140g

[0142] Add water to decoct rhubarb twice, each time adding 8 times the amount of water and decoct for 1 hour; After drying, the filtrate is concentrated to a relative density of about 1.25 (measured at 65-75°C), spray-dried into a dry extract powder; add appropriate amount of sucrose and dextrin to the above extract powder, mix well, make granules, and dry to obtain granules 1000g, that is to say.

Embodiment 2

[0143] Embodiment 2: dropping pill

[0144] Coptis 176g Rhubarb 533.3g Scutellaria baicalensis 266.7g

[0145] Preparation method: add the above three flavors, decoct twice with water respectively, the first time is 1.5 hours, and the second time is 1 hour, combine the decoction, filter, the filtrate is concentrated to 70°C, the relative density is about 1.25, add polyethylene glycol 4000 and polyethylene glycol In the base mixed with ethylene glycol 6000, drop into liquid paraffin at a certain speed, drain into pellets, and the product is obtained.

Embodiment 3

[0146] Embodiment 3: effervescent agent

[0147] Coptidis 150g Rhubarb 550g Scutellaria baicalensis 300g Paeonol 140g Phellodendron 150g

[0148] Preparation method: add the above five flavors, add water and decoct twice, the first time is 1.5 hours, and the second time is 1 hour, combine the decoction, filter, and the filtrate is concentrated to a thick paste with a relative density of about 1.25 at 70°C; polyethylene glycol After dissolving, add sodium bicarbonate, spray it into the thick paste, and press it into tablets together with sweetener and sour agent.

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Abstract

The invention discloses a pharmaceutical composition with the effects on eliminating heat, reducing fire and detoxifying, a preparation method and a quality control method thereof. The crude drugs of the pharmaceutical composition of the invention comprise coptis, Chinese rhubarb and scutellaria; the preparation method comprises the steps that: the three raw materials are respectively added with water and decocted for 2 to 3 times; for each time, 6 to 9 times of water is added and decoction is done for 1 to 2 hours; the decoction solutions of each raw material are mixed and filtered; the filtrate is condensed till obtaining an approximate relative density of 1.25 (measured under 65 to 75 DEG C), and then sprayed and dried to obtain dry extract; the three dry extracts are added with proper amount of cane sugar and dextrin, well mixed, pelletized and then dried so as to obtain 1000g of granules, and finished product is obtained. The invention adopts high performance liquid chromatography to determine the content of baicalin. The pharmaceutical composition of the invention has good effect on eliminating heat, reducing fire and detoxifying.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, a preparation method and a quality control method thereof, in particular to a traditional Chinese medicine composition with functions of clearing away heat, purging fire and detoxification, and a preparation method and a quality control method thereof. Background technique [0002] In recent years, with the improvement of people's living standards and the increase of work pressure, due to reasons such as overeating and greasy food and chaotic rhythm of life, the incidence of diseases with symptoms such as chronic pharyngitis and tonsillitis continue to rise, while the traditional Chinese medicine in the prior art All can not solve all the above-mentioned existing conditions, so it is urgent to find a medicine that can solve all the above-mentioned existing symptoms. [0003] The use of traditional Chinese medicine to treat such diseases can avoid the disadvantages of the above-mention...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K36/756A61P11/04A61P1/02A61P1/10G01N30/90G01N30/02
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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