31results about How to "Good identification specificity" patented technology

The invention relates to a traditional Chinese medicament combination for treating children pharyngolaryngitis, a preparation method and a quality control method thereof; and the medicament combination consists of raw herbal materials of honeysuckle, calculus bovis, blackberry lily, tinospora root, balloonflower and radix scrophulariae, etc. According to traditional Chinese medicament conventional technology, the raw herbal materials are prepared into various preparations suitable for clinical application, including tablets, capsules, oral liquid preparations, dropping pills, granules, etc. The quality control method comprises the qualitative identification of thin layer chromatography and the content determination of high performance liquid chromatography and the like. The medicament combination is used for treating influenza, upper respiratory tract infection, and swollen sore throat, erosion of mouth and tongue, cough with profuse sputum, pharyngitis and laryngitis, tonsillitis, fever and the like caused by lung excess heat with obvious curative effect.

The invention discloses a pharmaceutical composition with the effects on eliminating heat, reducing fire and detoxifying, a preparation method and a quality control method thereof. The crude drugs of the pharmaceutical composition of the invention comprise coptis, Chinese rhubarb and scutellaria; the preparation method comprises the steps that: the three raw materials are respectively added with water and decocted for 2 to 3 times; for each time, 6 to 9 times of water is added and decoction is done for 1 to 2 hours; the decoction solutions of each raw material are mixed and filtered; the filtrate is condensed till obtaining an approximate relative density of 1.25 (measured under 65 to 75 DEG C), and then sprayed and dried to obtain dry extract; the three dry extracts are added with proper amount of cane sugar and dextrin, well mixed, pelletized and then dried so as to obtain 1000g of granules, and finished product is obtained. The invention adopts high performance liquid chromatography to determine the content of baicalin. The pharmaceutical composition of the invention has good effect on eliminating heat, reducing fire and detoxifying.

The invention relates to the medicinal field, and concretely relates to a quality detection method for Huoxiang Zhengqi dripping pills. The quality detection method comprises an identification method and a content determination method, and the identification method comprises the steps of Atractylodes lancea identification, dahurian angelica root identification, cortex magnoliae officinalis and Pogostemon cablin oil thin-layer identification, Perilla frutescens leaf oil identification, dried orange peel identification, licorice identification and Pinellia Tuber idenfication and is carried out through using thin layer chromatography. The quality detection method also comprises the determination of the contents of effective components in the Huoxiang Zhengqi dripping pills, the effective components comprise hesperidins, magnolols and honokiols, and the content determination method is carried out through adopting high performance liquid chromatography.

The invention discloses a pharmaceutical composition for treating women menopausal syndrome, a preparation method and a quality control method. The pharmaceutical composition of the invention is composed of pharmaceutical raw materials of glossy privet fruit, palmleaf raspberry fruit, south dodder seed, tuber fleeceflower root, cortex lycii radicis, ladybell root, dwarf lilyturf tuber, baical skullcap root, rehmannia root, white paeony root, red paeony, Chinese angelica, nacre and blackend swallowwort root; the preparation method is that: the pharmaceutical raw materials are selected, ground into fine powder, screened and evenly mixed; every 100g of powder is added by 42g of refining honey and appropriate amount of water, pill making and low-temperature drying are carried out, thus preparing the pharmaceutical composition. The preparation method adopts high performance liquid chromatography to carry out the content measurement on paeoniflorin. The pharmaceutical composition of the invention has good efficacy for treating women menopausal syndrome.

The invention relates to a traditional Chinese medicine composition for treating insomnia and a preparation method and a quality control method thereof. The medicine composition comprises mother-of-pearl, Polygonum multiform, glossy privet fruit, Salvia miltiorrhiza and other bulk medicines. The preparation method is easy, simple and convenient, and can preserve effective components in the medicines and give play to the treatment effect of the medicines to the maximum degree. The quality control method comprises the steps of thin-layer identification of the Salvia miltiorrhiza, Schisandra chinensis, prepared rehmannia rhizome, the glossy privet fruit and Silktree Albizzia barks, content inspection of an ethanol extract, and content assay of an effective component tanshinone IIA in the medicines, and can effectively control the quality of the medicines and guarantee the stability of the treatment effect of the medicines.

The invention discloses a drug composition and a preparation method as well as a quality control method for curing hypertension. The drug composition comprises the following raw medicines of apocynum venetum, selfheal, uncaria, alisma orientale, mother-of-pearl, achyranthes, hawthorn and chrysanthemum. The preparation method is as follows: the raw medicine composition is filled with conventional accessories and is made into a clinically acceptable dosage form according to the conventional technology. The clinically acceptable dosage form includes concentrated pills, capsules, dropping pills, granules, tablets, soft capsules, slow-release formulation, oral liquid or freeze-dry powder injection. The invention controls the quality of products through the authentication of selfheal and apocynum venetum. The drug composition of the invention has good curative effects on hypertension.

The invention discloses a medicinal composition having effects of clearing heat, relieving fire and eliminating toxins and preparation and detection methods thereof. The medicinal composition is prepared from the following raw materials: coptsir root, Chinese teasel root and baikal skullcap root. The preparation method comprises the following steps of: adding water into the three raw materials for decoction for 2 to 3 times, wherein the amount of the added water is 6 to 9 times that of the raw materials and the decoction time is 1 to 2 hours for each time; combining decoction solution and filtering the mixed solution; concentrating filtrate to ensure that the relative density is about 1.25 (detected at the temperature of 65 to 75 DEG C); performing spray drying on the obtained product to obtain dry powdered extract; adding a proper amount of cane sugar and dextrine into the dry powdered extract; uniformly mixing the mixture; preparing the mixture into particles; and drying the particles to obtain 1,000g of particles so as to obtain the finished product. In the detection method, the content of baicalin is measured by high performance liquid chromatography. The medicinal composition has good effects of clearing the heat, relieving the fire and eliminating the toxins.

The invention discloses a pharmaceutical composition, a preparation method and a quality control method. The pharmaceutical composition of the invention is composed of pharmaceutical raw materials such as costustoot, villous amomum fruit, largehead atractylodes rhizome, tangerine peel, Indian buead, pinellia tuber (prepared), nutgrass galingale rhizome, immature bitter orange, jave amonum fruit, officinal magnolia bark, cablin potchouli herb and liquoric root; the prepration method is that: the pinellia tuber and fresh ginger take ethanol as solvent for immersion, and colation is used as standby; the costustoot, the villous amomum fruit, the largehead atractylodes rhizome, the tangerine peel, the immature bitter orange, the jave amonum fruit, the officinal magnolia bark and the cablin potchouli herb use the distillation method for extracting volatile oil, water solution after the distillation is collected in an another container; the medicine residues and other three medicines of Indian buead and the like, as well as Chinese date are decocted by adding water, the filtration is carried out, filtrate and the water solution are merged and concentrated to the relative density of 1.10, the mixture is cooled, ethanol is added, supernatant liquid is poured and taken, the filtration is carried out, the filtrate is merged with the filtrate, the ethanol is recycled, clear paste is obtained by concentration, the clear paste is taken for preparing granules, the volatile oil is added, and the pharmaceutical composition can be obtained by even mixing. The preparation method adopts high performance liquid chromatography to carry out the content measurement of costunolide. The pharmaceutical composition of the invention has significant effects of warming spleen and stomach and regulating stomach.

The invention discloses a pharmaceutical composition used for treating virus hepatitis, a preparation method and a quality control method thereof. The pharmaceutical composition has the raw materials of herba artemisiae capillaris, radix isatidis, rhizoma dryopteris crassirhizomae, indian bread, radix curcumae, herba scutellariae barbatae and patchouli, etc. The quality control method is that the traditional Chinese medicine provided by the invention is obtained by a great deal of creative experiments and screening as well as by the screening for a sample treatment method and the selection to a developing agent in a distinguishing method, and the distinguishing specificity is good; furthermore, the methods are economical and applicable, has rapid result and can be applied to different thin-layer plates. In a content measuring method, by the screening for a processing method of samples and test product and the selection to the developing agent, the content measuring method can effectively carry out quality control on products; furthermore, compared with other methods, the product measured by the method has more stable drug effect.

The invention discloses a pharmaceutical composition which has the effects of expelling wind, relieving the exterior, clearing heat and detoxifying, a preparation method and a quality control method thereof. The pharmaceutical composition of the invention consists of crude drugs as follows: patchouli, chrysanthemum, honeysuckle, dyer woad leaf, hedyotis diffusa, foxglove, tree peony bark, cynanchum atratum, mint and gypsum. The preparation method is characterized in that: water is added for decoction, the chrysanthemum, etc. is hot dipped, and the patchouli, the mint and water are used for extracting volatile oil which is condensed into clear paste. The pharmaceutical composition of the invention has good effects of expelling wind, relieving the exterior, clearing heat and detoxifying.

The invention discloses day lily flower and a method for detecting a day lily flower preparation. The method for detecting the day lily flower preparation comprises one or more the following identification methods and/or content measurement methods of: A, thin-layer chromatography identification; B, ultraviolet spectrophotometry content measurement; C, HPLC (High Performance Liquid Chromatography) content measurement; and D, HPLC fingerprint chromatography of an original medicinal material. The invention also further provides an HPLC detection method and an HPLC fingerprint chromatography detection method of the day lily flower. According to the day lily flower and the method for detecting the day lily flower preparation, which are disclosed by the invention, the identification specificity is good and the method is low in cost and is practical and is rapid in obtaining a result; the product can be effectively subjected to quality detection by the content measurement methods; and an analysis method in the fingerprint chromatography detection is stable, reliable and effective and the basis is provided for identification and quality evaluation and control of the day lily flower preparation and the medicinal material.

The invention discloses a pharmaceutical composition for treating skin pruritus, a preparation method and a quality control method thereof. The pharmaceutical composition of the invention consists of crude drugs as follows: fruit of Siberian cocklebur, puncture vine fruit, rhizoma ligustici wallichii, peach kernel and herb of bittersweet. The preparation method is characterized in that: water is added for decoction for 2 to 3 times and 1 to 3 hours for each time, decoction solution is mixed and kept standing for 7 to 9 hours for sedimentation, and supernatant fluid is taken and condensed into clear paste, the relative density of which is 1.36 (65 to 75 DEG C); one portion of the clear paste is taken, three portions of cane sugar powder, one portion of dextrin and a proper amount of ethanol are added to prepare granules which are dried and the pharmaceutical composition is prepared. High performance liquid chromatography is used for determining the content of forulic acid by the invention. The pharmaceutical composition of the invention has very good curing effect for skin pruritus.

The invention discloses a composition for relieving exterior syndrome and clearing away heat and toxic materials, and a preparation method and a detection method thereof. The medicinal composition comprises the following medicinal raw materials: cablin patchouli herb, chrysanthemum, honeysuckle flower, indigowoad leaf, spreading hedyotis herb, rehmannia root, tree peony bark, blackend swallowwort root, mint and gypsum. The detection method has high specificity and is economical and practical, and a result can be quickly obtained.

The invention relates to the field of drugs, in particular to a preparation method and testing method of tablets for treating gouty arthritis. The testing method is obtained through screening with creative experiments, and in the testing method, through the screening of sample treatment methods and the selection of a developing solvent system, distinguishing specialization is good, the testing method is economical and applicable, a result can be quickly obtained, and the defects that existing thin-layer identification of cassia twig and cortex acanthopanacis has no specialization are overcome.In a content testing method, the test of the astragaloside content is added through the optimization of the test sample treatment methods, so that the quality of the product can be effectively controlled by means of the content testing method, and the practical production requirements can be met.

The invention provides a heat-clearing eight-ingredient pill detection method, which belongs to the field of medicine analysis. The existing quality standard of heat-clearing eight-ingredient pills iscorrespondingly improved, and a method of distinguishing Hu Huanglian and Kudingding with strong specificity is added on the basis of the original quality standard, and a method of measuring the content of hydroxysafflor yellow A is added. The method has the characteristics of simplicity, fast speed, good reproducibility and the like. The established identification and content measurement methodsmeet relevant requirements through methodological verification, have strong applicability, can more comprehensively reflect the product quality status and provide an important basis for quality control and standard setting.

The invention discloses a Chinese medicine composite for regulating qi, widening chest and relieving pain and for treating stenocardia and abdominal distending pain as well as a quality control method thereof. The Chinese medicine composite is a pill made from raw medicinal materials of storax, borneol, frankincense, agilawood and radix aucklandiae. The quality control method comprises the steps of thin-layer identification of the frankincense and the borneol and content determination of the borneol and can more comprehensively control the quality of drugs in qualitative and quantitative aspects. Pharmacodynamics tests show that the Chinese medicine composite provided by the invention has better treatment effect on treating the stenocardia and the abdominal distending pain.

The invention discloses a method for detecting a medicinal composition for treating viral hepatitis. The medicinal composition is prepared from the following raw material medicaments: virgate wormwood herb, indigowoad root, male fern rhizome, Indian buead, root-tuber of aromatic turmeric, barbed skullcap herb, patchouli and the like. The method for detecting the medicinal composition is obtained by screening a great number of specific creative tests. In an identification method, the identification specificity is high by screening sample processing methods and selecting a developing solvent; and the method is economic and practical, is used for quickly acquiring results and can be applied to different thin layer plates. In a content detecting method, the quality of products can be effectively controlled by screening samples and sample supply processing methods and selecting the developing solvent. The products detected by the method have more stable medicinal effects than products detected by other methods.

The invention relates to the technical field of biology, in particular to a reagent for identifying ovarian endometriosis/other ovarian benign tumors and application of the reagent. The invention provides application of a reagent for detecting the content of a biomarker in a subject sample in preparation of a product for differential diagnosis of ovarian endometriosis/other ovarian benign tumors. The biomarkers comprise CA125, SELL, LILRA3, IGKC and/or DSC2 (Differentiated Sequence Cells). The invention also provides a marker CA125, SELL, LILRA3, IGKC and/or DSC2 for differential diagnosis of ovarian endometriosis/other ovarian benign tumors, can be used for preparing a detection kit and the like for differential diagnosis of EM/FEM, and has good identification specificity and high sensitivity. By adopting the kit, the accuracy of clinical EM/FEM differential diagnosis can be improved, so that a patient can obtain more accurate treatment measures, and a better treatment effect is obtained.