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Traditional Chinese medicine composition for regulating qi-flowing and relieving chest stuffiness and pain

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, active ingredient of hydroxyl compound, pharmaceutical formula, etc., can solve problems such as large side effects, difficult to achieve fundamental treatment, etc., and achieve the effects of rapid results, effective quality control, and good identification specificity.

Active Publication Date: 2011-05-25
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Nitrate drugs, calcium ion antagonists, and β-receptor blockers are commonly used in clinical treatment and control of angina pectoris, but these drugs have relatively large side effects and are difficult to achieve the purpose of fundamental treatment

Method used

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  • Traditional Chinese medicine composition for regulating qi-flowing and relieving chest stuffiness and pain
  • Traditional Chinese medicine composition for regulating qi-flowing and relieving chest stuffiness and pain
  • Traditional Chinese medicine composition for regulating qi-flowing and relieving chest stuffiness and pain

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0090]Preparation of the test solution: Take 1 g of this product, put it in a mortar, add 5-10 ml of ether, grind, filter, put the filtrate in an evaporating dish, evaporate the ether, cover the watch glass, heat it on a water bath, and collect the sublimation , add ethanol 1ml to dissolve, as the test solution.

[0091] Preparation of reference substance solution: take borneol reference substance, add ethanol to make a solution containing 1mg per 1ml, as the reference substance solution.

[0092] Preparation of negative reference substance solution: prepare a negative reference substance lacking borneol according to the preparation method of the test sample, and then prepare a negative reference substance solution according to the preparation method of the test sample solution.

[0093] A. The choice of developer

[0094] Test according to thin-layer chromatography (Appendix VIB, Chinese Pharmacopoeia, 2005 Edition), draw 3 μl of the above-mentioned test solution and referen...

Embodiment 1

[0140] Take the following parts by weight (g) bulk drug:

[0141] Styrax 65g, borneol 125g, frankincense (made) 95g, agarwood 165g, woody 235g

[0142] The above five flavors, except storax and borneol, add 10 times the amount of water to extract the volatile oil of the other three flavors such as frankincense, and extract the dregs with 4 times the amount of 80% ethanol under reflux for two times, each time for 2 hours, filter, and recycle the ethanol from the filtrate to nothing Alcoholic taste, concentrated under reduced pressure to a thick paste with a relative density of 1.25-1.30, dried, crushed into fine powder, added styrax, borneol and 220g of polyethylene glycol 6000 base, heated until dissolved, then added the above-mentioned frankincense and other volatile oils, and mixed well , made into 450g dropping pills, to get final product.

Embodiment 2

[0144] Take the following parts by weight (g) bulk drug:

[0145] Artificial musk 35g, borneol 125g, frankincense (made) 95g, sandalwood 165g, inulin 235g

[0146] The above five flavors, except artificial musk and borneol, add 10 times the amount of water to extract the volatile oils of the other three flavors such as frankincense, and extract the dregs with 4 times the amount of 80% ethanol by heating and refluxing twice, each time for 2 hours, filter, and the filtrate recovers ethanol to No alcohol smell, concentrated under reduced pressure to a thick paste with a relative density of 1.25-1.30, dried, crushed into fine powder, added styrax, borneol and 220g of polyethylene glycol 6000 base, heated until dissolved, then added the above-mentioned frankincense and other volatile oils, mixed Evenly, make 430g dropping pills, to get final product.

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Abstract

The invention discloses a traditional Chinese medicine composition used for regulating qi-flowing, relieving chest stuffiness and pain and curing angina and abdominal pain and a quality control method thereof. The traditional Chinese medicine composition is a dripping pill prepared by taking storax, borneol, frankincense, tambac and costus root as raw materials. The quality control method thereofcomprises the steps of the lamella identification of the frankincense and the borneol and the content measurement of the borneol and can carry out more comprehensive quality control from the qualitative aspect and the quantitive aspect. The pharmacodynamic experiment shows that the invention has better curing efficacy for curing angina and abdominal pain.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a quality control method thereof, in particular to a traditional Chinese medicine composition for regulating qi, broadening the chest and relieving pain and a quality control method of the traditional Chinese medicine composition, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Angina pectoris is a clinical syndrome caused by coronary insufficiency, myocardial acute, temporary ischemia and hypoxia. It is characterized by paroxysmal chest squeezing pain, which may be accompanied by other symptoms. The pain is mainly located at the back of the sternum and can radiate to the precordium and left upper limb. It often occurs during labor or emotional agitation and lasts for several minutes. Disappears with rest or with nitrate preparations. This disease is more common in men, and most patients are over 40 years old. Fatigue, emotional agit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/835A61K36/324A61K36/54A61K9/20A61P9/10A61P1/00G01N30/90G01N30/38G01N30/02A61K31/045A61K35/55
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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