Use of traditional Chinese medicine in preparing medicine for treating myocardial infarction

A technology of myocardial infarction and composition, applied in the field of application of traditional Chinese medicine composition in the preparation of medicines for treating myocardial infarction

Active Publication Date: 2008-11-19
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many clinical trials have confirmed that artificial intervention in this process and delaying its progress will bring huge benefits to MI patients

Method used

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  • Use of traditional Chinese medicine in preparing medicine for treating myocardial infarction
  • Use of traditional Chinese medicine in preparing medicine for treating myocardial infarction
  • Use of traditional Chinese medicine in preparing medicine for treating myocardial infarction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Embodiment 1: the preparation of medicine of the present invention

[0066] prescription:

[0067] Astragalus 450g Aconite 112.5g Ginseng 225g Salvia miltiorrhiza 225g Tinglizi 150g

[0068] Xiangjia skin 180g Alisma 225g safflower 90g Polygonatum 75g Chenpi 75g Guizhi 90g

[0069] Preparation:

[0070] (1) Radix Astragali, Tinglizi, Alisma, Ginseng, Cyperus bark were extracted twice according to the above prescription plus 8 times the amount of 70% ethanol under reflux, the first time was 3 hours, the second time was 2 hours, the extracts were combined, filtered After passing through, the filtrate is decompressed to recover ethanol, and is concentrated to a clear paste with a relative density of 1.25-1.30 (60°C thermal measurement), for subsequent use;

[0071] (2) Guizhi and tangerine peel are distilled to extract volatile oil according to the proportion, the aqueous solution after oil extraction is filtered, and set aside, and the residue is decocted with 8 times ...

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Abstract

The invention discloses the application of a Chinese traditional medicinal combination in preparing the medicaments used for curing myocardial infarction. The Chinese traditional medicinal combination inhibits the activity of matrix metalloproteinase, the damage to the heart support structure, the progressive ventricular dilatation, and the change of gene phenotype of the heavy chain of myosin of the cardiac muscle during the reversion of the restructuring of the cardiac muscle, thus inhibiting the restructuring of the cardiac muscle after myocardial infarction, improving the function of heart after myocardial infarction so that sufferers of myocardial infarction benefit from the Chinese traditional medicinal combination clinically, or the prognoses of myocardial infarction is improved.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in preparing a medicine for myocardial infarction. Background technique [0002] Myocardial infarction (MI) is coronary artery occlusion, blood flow interruption, causing partial necrosis of myocardium due to severe and persistent ischemia. In European and American countries, about 800,000 people suffer from myocardial infarction and 450,000 suffer re-infarction every year. This disease is increasing year by year in my country. Because myocardial loss causes an irreversible myocardial remodeling process, eventually to heart failure and death, it seriously threatens people's health (Chen Haozhu "Practical Internal Medicine" People's Health Publishing House, July 1997, 10th Edition, page 1237-1238). [0003] Myocardial remodeling is the basic pathological process after myocardial infarcti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/08A61K9/10A61K9/14A61K9/20A61K9/48A61P9/10
Inventor 吴以岭廖玉华
Owner HEBEI YILING MEDICINE INST
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