Unlock instant, AI-driven research and patent intelligence for your innovation.

4-oxadiazolyl-piperidine compounds and use thereof

A compound and alkyl technology, applied in the field of 4-oxadiazolyl piperidine compounds, can solve the problems of increased drug tolerance, increased drug dependence, respiratory depression and the like

Inactive Publication Date: 2008-11-26
PURDUE PHARMA LP
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this crossing of the blood-brain barrier can lead to unwanted CNS-mediated side effects such as respiratory depression, increased drug tolerance, increased drug dependence, constipation, and unwanted euphoria

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • 4-oxadiazolyl-piperidine compounds and use thereof
  • 4-oxadiazolyl-piperidine compounds and use thereof
  • 4-oxadiazolyl-piperidine compounds and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

4-Oxadiazolyl-piperidine compounds of formula (I) and (II), their compositions and use for the treatment of pain and diarrhoea.

Description

1. Technical field The present invention relates to 4-oxadiazolylpiperidine compounds, compositions comprising 4-oxadiazolylpiperidine compounds and methods for preventing or treating pain or diarrhea in animals, the method comprising administering to animals in need of such prevention or treatment An effective amount of a 4-oxadiazolylpiperidine compound. 2. Background technology Pain is the most common symptom for which patients seek medical guidance and treatment. Pain can be acute or chronic. Acute pain is usually self-limited, whereas chronic pain can persist for 3 months or more and result in significant changes in the patient's personality, lifestyle, ability to live, or overall quality of life (K.M. Foley, Pain, in Cecil Textbook of Medicine 100-107, J.C. Bennett and F. Plum eds., 20th ed. 1996). Pain is traditionally managed by administering non-opioid pain relievers such as acetylsalicylic acid, choline magnesium trisalicylate, acetaminophen, ibuprofen, fenopro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07D413/04C07D413/14A61K31/454A61P25/00
CPCC07D413/04C07D413/14A61P1/12A61P25/00A61P25/04A61P43/00A61K31/454
Inventor 莱基·塔费塞
Owner PURDUE PHARMA LP