Method for cascade mass spectrometry by using multiple ion traps
A tandem mass spectrometry and ion trap technology, which is applied in the direction of material analysis, mass spectrometer, and material analysis by electromagnetic means, can solve the problems of limited length, small ion storage capacity, and inability to meet high-throughput tandem mass spectrometry analysis, etc. Achieve the effect of reducing instrument production cost, improving sensitivity and analysis efficiency
Inactive Publication Date: 2008-12-10
FUDAN UNIV +1
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That is to say, the length of a resonant ion trap will be very limited, so its ion storage capacity will be
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Abstract
The invention belongs to the quality analysis technology field and in particular relates to a method of using a plurality of ion traps for the tandem mass spectrometric analysis, including that a high frequency capturing electric field based on a quadrupole field is produced in the first ion trap for capturing ions with various mass-to-charge ratios. A dipolar excitation alternating electric field with certain frequency along the direction of a straight line for connecting the center of the first ion trap center with the center of a second ion trap center is produced in the first ion trap. Thus, the ions with a mass-to-charge ratio oscillate along the direction to reach to the large amplitude under the resonance excitation. Furthermore, a discharged pulse electric field generates in a specific phase of the first ion trap. The ions reaching to the large moving amplitude are discharged and enter the second ion trap. And the ions with other mass-to-charge ratios are still left in the first ion trap. Through a deceleration field added in the second ion trap or the gas collision, the entering ions or byproduct ions are captured and the researching analysis is further made in the second ion trap.
Description
technical field [0001] The invention belongs to the technical field of mass analysis, and in particular relates to a method for mass analysis of ions using two or more ion traps. technical background [0002] Mass spectrometer is a scientific instrument that can be used to analyze various components, contents and molecular structures in material samples. Ion trap mass spectrometer is one of the mass spectrometers widely used at present. It has the characteristics of simple structure, convenient operation and relatively cheap price. It is widely used in various fields such as chemistry, life science, geological science, petrochemical industry, medicine and health, environmental protection, food safety, etc. [0003] Traditional ion traps can be divided into three-dimensional ion traps and linear ion traps according to their different structures. The shape of the electrode constituting the ion trap includes a hyperbolic electrode, a cylindrical electrode, or a rectangular e...
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IPC IPC(8): G01N27/64H01J49/26
CPCH01J49/423H01J49/004H01J49/427
Inventor 蒋公羽罗婵丁传凡丁力
Owner FUDAN UNIV
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