The invention discloses a micro-domain laser probe component analyzer based on optical fiber waveguide. The analyzer comprises a Nd:YAG laser, a wavelength-tunable laser, a CCD monitoring camera, a computer, a grating spectrometer, a focusing objective lens, a displacement platform, a digital delay pulse generator, and an enhanced CCD. The focusing lens is a reflective focusing lens. The Nd:YAG laser and the wavelength-tunable laser both adopt optical fiber waveguide for carrying out laser pulse transmission; laser pulse is collimated by using an optical fiber collimator and expanded by a beam expander, and enters the focusing objective lens. Laser pulse transmitted by the Nd:YAG laser burns a surface micro-domain on a sample to be analyzed, such that plasma is formed; the laser pulse transmitted by the wavelength-tunable laser is applied on the plasma, such that resonance excitation is caused; one end of the optical fiber is used for collecting spectral signal transmitted by the plasma, and the other end is connected with an optical fiber interface of the grating spectrometer. According to the invention, precise qualitative and quantitative analysis of laser probe upon substance micro-domain components can be realized.