A novel process for the manufacture of 5-nonyl salicylaldoxime
A technology of nonyl salicylaldoxime and catalyst, applied in the field of preparation of 5-nonylsalicylaldoxime, which can solve the problems of high cost and difficult sewage treatment
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example 1
[0028] Place a 2-liter round-bottom 4-necked flask in a suitable heating mantle, equipped with a stirrer, reflux condenser, thermometer and dropping funnel, and fill it with 83g of toluene, 12.6g (0.525mol) of magnesium powder, 0.06 g iodine, 2.7 g anhydrous tin dichloride. In this way, under stirring conditions, 272 g of toluene methanol azeotrope was slowly added to the previously obtained mixture. The reaction mixture was heated to reflux temperature (approximately 64°C) for 60 minutes to ensure complete formation of magnesium alkoxide. Slowly add 220 g (1.0 mol) of nonylphenol and continue refluxing for another hour. 265 g of toluene was added, and the temperature rose to 80°C, at which temperature the toluene methanol azeotropic mixture began to distill. The distillation continues until all the azeotrope is distilled out.
[0029] Further, 0.9 g of tin dichloride was added to the above reaction amount, and 33 g (0.36 mol) of paraformaldehyde powder was added through the s...
example 2
[0036] Repeat the above experiment, replacing the previously added 2.7g and 0.9g with 4.05g and 1.35g tin dichloride. The purity of the product obtained by GC is about 90%. The percentage difference is due to the formation of more contaminants compared to Example 1.
example 3
[0038] Repeat Example 1, using 1.35g and 0.45g tin dichloride instead of the added 2.7g and 0.9g. The purity of the product obtained by GC is 92%, which is due to the presence of unreacted nonylphenol.
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