Foamed substrate and method for making same

Abstract

The present invention provides a foamed and / or aerated substrate for transmucosal and / or transdermal applications. The foamed and / or aerated substrate may be in the form of a film, sheet, strip or wafer. The foamed and / or aerated substrate is suitable for use in applications such as, for example, adhesive denture liners, tooth whitening, and smoking control / cessation. The foamed and / or aerated substrate is polymeric in nature and comprises one or more polymers and one or more foaming agents. Additionally, the foamed and / or aerated substrate may include, but not limited to, one or more plasticizers, hydrophobic barrier agents, tooth whitening agents, antioxidants, preservatives, super-disintegrants or absorbents, flavorants, deodorants, breath freshening agents, colorants, surfactants, film modifiers, cross-linking agents, antimicrobial agents, control release agents, other therapeutic agents, or any combinations thereof.

Description

technical field

[0001] The present invention relates to foam substrates. More specifically, the present invention relates to foams and / or gas-filled films for transmucosal and transdermal use. Background technique

[0002] The use of polymer-based transmucosal and / or transdermal films to deliver one or more active ingredients is known in the art. Some of the disadvantages associated with these films include, but are not limited to, being stiff, heavy, unsightly and uncomfortable to the user.

[0003] Although advances have been made in the use of polymer-based transmucosal and / or transdermal membranes to deliver one or more active ingredients, the search for more effective materials continues. There remains a strong need to find a film that is strong and effective enough to withstand use in a transmucosal and / or transdermal environment, while being relatively comfortable for the user during use. The present invention meets and / or exceeds this need. Summary of the invent...