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Traditional Chinese medicine preparation for treating hepatitis B

A technology of traditional Chinese medicine preparation and hepatitis B, applied in the direction of medical preparations containing active ingredients, antiviral agents, drug combinations, etc., can solve the problems of immune tolerance or low immune function, and achieve the effect of less adverse reactions and low cost

Inactive Publication Date: 2009-03-18
THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most scholars believe that the main mechanism of HBV infection chronicity is that the host produces different degrees of specific immune response to various HBV antigens, that is, immune tolerance or low immune function.

Method used

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  • Traditional Chinese medicine preparation for treating hepatitis B
  • Traditional Chinese medicine preparation for treating hepatitis B
  • Traditional Chinese medicine preparation for treating hepatitis B

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 Chinese medicine preparation

[0025] Ephedra 8g Aconite 6g Asarum 3g

[0026] Dried Ginger 9g Horn Thorn 12g White Back Leaf Root 20g

[0027] Atractylodes 12g Bupleurum 12g Citrus aurantium 15g

[0028] 9g peach kernel, 9g safflower, 30g astragalus

[0029] Angelica 15g Epimedium 15g Centipede 4g.

[0030] Mix the above components into a medicinal pot, add 500ml of water, and decoct for 45 minutes to obtain a concentrated extract.

[0031] One dose per day, taken before meals, every 3 months as a course of treatment, before treatment, record the patient’s four diagnostic data of traditional Chinese medicine, and check the blood routine, four coagulation items, liver function, AFP, HBeAg(imx), HBV-DNA quantitative, liver and gallbladder Ultrasound of pancreas and spleen and chest X-ray, and it is recommended that patients undergo liver histopathological examination. After each course of treatment, recheck liver function, HBeAg(imx), ...

Embodiment 2

[0032] Embodiment 2 drug efficacy experiment:

[0033] 1 Research object

[0034] Patients with chronic hepatitis B who visited the Department of Traditional Chinese Medicine of the Third Affiliated Hospital of Sun Yat-sen University and the Department of Infectious Diseases of Jiangyin People's Hospital affiliated to Southeast University School of Medicine from January 2000 to April 2002 were selected as the research objects.

[0035] 1.1 Diagnostic criteria:

[0036] The "Diagnostic Criteria for Viral Hepatitis" jointly revised by the Infectious Diseases and Parasitic Diseases Branch of the Chinese Medical Association and the Hepatology Branch in September 2000 was adopted. TCM syndrome differentiation standard was formulated by the Tianjin Conference in 1991, "Viral Hepatitis TCM Syndrome Differentiation Standard (Trial)".

[0037] 1.2 Inclusion criteria

[0038] (1) Patients who meet the diagnostic criteria and are diagnosed with mild or moderate chronic type B.

[003...

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Abstract

The invention discloses a preparation of traditional Chinese medicines for treating chronic hepatitis B, which is prepared by the following components according to weight percentage: 6-12 percent of Chinese ephedra, 3-9 percent of monkshood, 3-6 percent of asarum, 6-9 percent of dried ginger, 12 percent of Chinese honeylocust spine, 15-30 percent of white backleaf mallotus root, 11-13 percent of Chinese atractylodes, 11-13 percent of radix bupleuri, 14-16 percent of bitter orange, 8-10 percent of peach seed, 8-10 percent of safflower, 29-31 percent of radix astragali, 14-16 percent of angelica, 12-18 percent of herba epimedii and 3-6 percent of scolopendra. In the invention, Chinese medicine treatment is adopted in the early period to positively cure the disease, adjust immunity function of HBV infection patients, excite the immunity of the organism of chronic HBV carriers, break the state of immune tolerance and adjust the immunity function of the patients who suffer from HBeAg masculine minor chronic hepatitis B, thus improving clinical symptoms and physical sign of the two patients, shortening the course of disease of the patients and increasing the negative turning rate of HBeAg and HBV-DNA thereof, therefore, clinical curative effect on treating patients infected by HBV with the traditional Chinese medicine is improved and the curative effect on hepatitis B is enhanced.

Description

technical field [0001] The invention relates to a medicine for treating hepatitis B. Background technique [0002] HBV infection is a worldwide epidemic. According to the report of the World Health Organization, about 2 billion people in the world have been infected with HBV, of which 350 million people are chronic HBV infected people, and about 1 million people die every year from liver failure, liver cirrhosis and primary hepatocellular carcinoma caused by HBV infection (HCC). my country is a high prevalence area of ​​HBV infection, and the positive rate of HBsAg in the general population is 9.09%. [0003] The overall goals of chronic hepatitis B treatment are: maximal long-term suppression or elimination of HBV, reduction of liver cell inflammation and necrosis and liver fibrosis, delay and prevention of disease progression, reduction and prevention of liver decompensation, liver cirrhosis, HCC and their complications symptoms, thereby improving quality of life and pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/16A61P31/20A61K35/64A61K35/648
Inventor 杨宏志谢和平
Owner THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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