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A technology of apramycin sulfate and injection, which is applied in the field of compound apramycin sulfate injection, can solve the problems of reducing the curative effect, increasing the dosage, and excessive pork drug residues, etc. The effect of drug resistance
Inactive Publication Date: 2009-05-06
TIANJIN SHENGJI GRP CO LTD
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Summary
Abstract
Description
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Problems solved by technology
[0005] Due to the long-term repeated use of an antibiotic or antibacterial drug, the pathogenic microorganisms have developed resistance to the drug and the curative effect has been reduced. In order to obtain the curative effect, the dose must be increased, so that the drug residue in pork exceeds the standard
Method used
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Effect test
Embodiment 1
[0015] 1. Add 20kg of sodium salicylate to 30L of water for injection, then add 4kg of acetylmethaquine, and stir for 10-25min until the solution is clear;
[0016] 2. Take 30L of water for injection, add 10kg of apramycin sulfate, 0.7kg of atropine sulfate, and 0.5kg of chlorpheniramine maleate in sequence and stir to dissolve;
[0017] 3. Combine the solution prepared in step 1 and step 2 and add water for injection to 100L, stir evenly, keep for 15-20min, and make it after the liquid medicine is clarified.
Embodiment 2
[0019] 1. Add 20kg of sodium salicylate to 30L of water for injection, then add 5kg of acetylmethaquine, and stir for 10-25min until the solution is clear;
[0020] 2. Take 30L of water for injection, add 9kg of apramycin sulfate, 0.4kg of atropine sulfate, and 0.3kg of chlorpheniramine maleate in sequence, and stir to dissolve;
[0021] 3. Combine the solution prepared in step 1 and step 2, add water for injection to 100L, stir evenly, keep for 15-20min, and make it after the liquid medicine is clarified.
Embodiment 3
[0023] 1. Add 20kg of sodium salicylate to 30L of water for injection, then add 6kg of acetylmethaquine, and stir for 10-25min until the solution is clear;
[0024] 2. Take 30L of water for injection, add 8kg of apramycin sulfate, 0.5kg of atropine sulfate, and 0.2kg of chlorpheniramine maleate in sequence and stir to dissolve;
[0025] 3. Combine the solution prepared in step 1 and step 2, add water for injection to 100L, stir evenly, keep for 15-20min, and make it after the liquid medicine is clarified.
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Abstract
The invention discloses a veterinary compound apramycin sulfate injection which can prevent pathogenic organisms from generating drug resistance. The invention belongs to medical products which contain organic effective components. Every 1000L of the compound apramycin sulfate injection is prepared by the materials as follows: 100 to 400kg of sodium salicylate and 20 to 100kg of maquindox are added into 300L of injection water in turn, stirred for 10 to 25min until the mixture is clear; then 30 to 120kg of apramycin sulfate, 1 to 20kg of atropine sulfate and 1 to 20kg of chlorphenamine maleate are added into another 300L of the injection water in turn, stirred and dissolved; then after the two obtained liquids are combined, the injection water is added to 1000L, fully stirred and maintained for 15 to 20min; and after the medicine liquid is clear, the veterinary compound apramycin sulfate injection is obtained. The invention adopts a compound preparation, is highly effective to the bacterial diarrhea of pig, treats both the symptom and root cause of diseases and eases the body stress response of an affected animal.
Description
technical field [0001] The invention relates to a pharmaceutical product containing organic active ingredients, or an anti-infection veterinary drug, specifically a compound apramycin sulfate injection Background technique [0002] Bacillary dysentery is a highly susceptible disease in pigs, which can cause diarrhea and diarrhea in pigs, and in severe cases, can cause death of pigs. [0003] The main pathogenic bacteria of this disease are Escherichia coli, Clostridium welchii, etc., which can cause severe diarrhea in pigs and are contagious. Large-scale infection will bring great losses to the pig breeding industry. In the past, macrolides or quinolones were often used as the first choice for the treatment of porcine bacillary dysentery. [0004] Apramycin sulfate commonly used clinically is an aminoglycoside antibiotic. It has antibacterial effect on Gram-negative bacteria such as Escherichia coli, Bacillus aerogenes, Klebsiella, and Proteus mutans. Antibiotics mainly u...
Claims
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Application Information
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