Chinese medicinal composition for treating hyperlipemia and preparation thereof

A technology for hyperlipidemia and medicine, which is applied in the field of medicine for the treatment of hyperlipidemia and its preparation, can solve the problems of unstable curative effect, weakened antibody, delayed treatment period of patients, etc., so as to reduce the oxygen consumption of the body and reduce the absorption , lower cholesterol and triglyceride effect

Inactive Publication Date: 2009-05-13
肖永雪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] According to our treatment and observation of hyperlipidemia over the past few years, we found that western medicine mostly adopts the method of lowering blood pressure and lowering blood fat in the treatment of hyperlipidemia, which does have a certain effect, but most patients will experience symptoms such as gastrointestinal discomfort after taking it for a long time. , increased aminotransferase, muscle weakness, dizziness, skin itching and other side effects, and the curative effect is not constant, thus delaying the best treatment period for patients, inducing artificial weakening of antibodies, leaving invisible hidden dangers

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1) Take 150g Panax notoginseng and crush it into 100 mesh fine powder, take 200g ginkgo leaf and 200g hawthorn leaf and crush it into coarse powder, use ethanol as solvent for percolation, collect the filtrate to recover ethanol under reduced pressure, add an equal amount of water to dilute, add Remove the pigment with petroleum ether, separate the water layer, shake and extract with ethyl acetate, recover the ethyl acetate under reduced pressure from the extract, and concentrate to dryness;

[0028] 2) 230g cassia seed, 230g turmeric, 200g trichosanthemi, 150g salvia miltiorrhiza, 150g Alisma 150g, 200g Radix Polygoni Multiflori, reflux twice with 80% ethanol, 4 hours for the first time, 3 hours for the second time, combine the filtrates, recover the ethanol, reduce Concentrate under pressure into a 50°C clear paste with a relative density of 1.40;

[0029] 3) The above-mentioned medicinal residues after alcohol extraction are combined and decocted in water for three t...

Embodiment 2

[0031] 1) Take 160g Panax notoginseng and crush it into 100 mesh fine powder, take 230g of ginkgo leaves and 230g of hawthorn leaves and crush them into coarse powder, use ethanol as solvent for percolation, collect the filtrate to recover ethanol under reduced pressure, add an equal amount of water to dilute, add Remove the pigment with petroleum ether, separate the water layer, shake and extract with ethyl acetate, recover the ethyl acetate under reduced pressure from the extract, and concentrate to dryness;

[0032] 2) 260g of cassia seed, 260g of turmeric, 230g of trichosanthemi, 160g of salvia miltiorrhiza, 170g of Alisma, 230g of Polygonum multiflorum, reflux twice with 80% ethanol, for the first time for 4 hours, for the second time for 3 hours, combine the filtrates, recover the ethanol, reduce Concentrate under pressure into a 50°C clear paste with a relative density of 1.40;

[0033] 3) The above-mentioned medicinal residues after alcohol extraction are combined and ...

Embodiment 3

[0035] 1) Take 170g Panax notoginseng and crush it into 100 mesh fine powder, take 260g of ginkgo leaves and 260g of hawthorn leaves and crush them into coarse powder, use ethanol as solvent for percolation, collect the filtrate to recover ethanol under reduced pressure, add an equal amount of water to dilute, add Remove the pigment with petroleum ether, separate the water layer, shake and extract with ethyl acetate, recover the ethyl acetate under reduced pressure from the extract, and concentrate to dryness;

[0036] 2) 290g cassia seed, 290g turmeric, 260g trichosanthemi, 170g salvia miltiorrhiza, 190g Alisma 190g, 260g Radix Polygoni Multiflori are refluxed twice with 80% ethanol, the first time is 4 hours, the second time is 3 hours, the filtrates are combined, ethanol is recovered, and the ethanol is reduced. Concentrate under pressure into a 50°C clear paste with a relative density of 1.40;

[0037] 3) The above-mentioned medicinal residues after alcohol extraction are ...

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PUM

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Abstract

The invention relates to a drug for treating hyperlipidemia and a preparation method thereof. The drug is prepared by the following pharmaceutical raw materials: ginkgo leaf, hawthorn leaf, cassia seed, turmeric root-tuber, Mongolian snakegourd root, danshen root, sanchi, oriental waterplantain rhizome and prepared tuber fleeceflower root. The preparation steps thereof are as follows: 1) the sanchi is taken and smashed into fine powder, the ginkgo leaf and the hawthorn leaf are additionally taken and smashed into coarse powder, the percolation is carried out, percolate is collected, the recovery of ethanol with the reduced pressure is carried out, then the dilution, the removal of pigments and the separation of a water layer are carried out, ethyl acetate is used for shaking extraction, and the ethyl acetate is recovered with the reduced pressure from extract liquid and concentrated till the ethyl acetate is dry; 2) the cassia seed, the turmeric root-tuber, the Mongolian snakegourd root, the danshen root, the oriental waterplantain rhizome and the prepared tuber fleeceflower root are taken, 80 percent ethanol is used for reflux for two times, filtrate is merged, and the ethanol is recovered and vacuum-concentrated to a clear paste with the relative density of 1.40 and the temperature of 50 DEG C; and 3) the various medicine residues after the ethanol extraction are merged, then water is added for carrying out three times of decoction, decocted liquid is merged and filtered, then the standing is carried out, supernatant fluid is taken and concentrated to a thick paste, an extract of the step 2 and the sanchi powder are further added for even mixing, the mixture is dried at the temperature of 60 DEG C and then ground to the fine powder with 100 meshes, and the packaging into capsules with 0.5g is finally carried out for preparation.

Description

technical field [0001] The invention relates to a medicine for treating hyperlipidemia, in particular to a medicine for treating hyperlipidemia prepared from Chinese herbal medicines and a preparation method thereof. Background technique [0002] According to our treatment and observation of hyperlipidemia over the past few years, we found that western medicine mostly adopts the method of lowering blood pressure and lowering blood fat in the treatment of hyperlipidemia, which does have a certain effect, but most patients will experience symptoms such as gastrointestinal discomfort after taking it for a long time. , increased transaminase, muscle weakness, dizziness, skin itching and other side effects, and the curative effect is not constant, thus delaying the best treatment period for patients, inducing artificial weakening of antibodies, leaving invisible hidden dangers. Contents of the invention [0003] The purpose of the present invention is to improve and innovate on...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P3/06
Inventor 肖永雪
Owner 肖永雪
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