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Medicament composition for treating hepatopathy and preparation method thereof

A technology of composition and medicine, which is applied in the field of traditional Chinese medicine composition and its preparation process, to achieve the effects of improving dissolution rate, reducing dosage and improving bioavailability

Active Publication Date: 2009-06-24
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Another object of the present invention is to develop a method for preparing a pharmaceutical composition for treating liver diseases with excellent performance and in line with the standards of the Pharmacopoeia of the People's Republic of China by utilizing the thirteen medicinal materials in the composition as raw materials, and overcoming the prior art The shortcoming of high production cost improves product quality, reduces cost, is convenient to take, and better meets medical needs

Method used

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  • Medicament composition for treating hepatopathy and preparation method thereof
  • Medicament composition for treating hepatopathy and preparation method thereof
  • Medicament composition for treating hepatopathy and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0075] Magnolia officinalis 20g, Rhizoma Chuanxiong 25g, Rhizoma Cyperi 31.4g, Paeoniae Alba 25g, Bupleurum 31.5g, Citrus aurantium 20g, Curcuma 25g, Bergamot 31.4g, Woody 15g, Chenpi 31.5g, Licorice 10g, Corydalis 60g, Malancao 150g of thirteen herbs as raw materials;

[0076] The above-mentioned thirteen raw materials are pulverized into fine powder passing through a 100-mesh sieve, dried at a controlled temperature of 55° C., and mixed uniformly to obtain a powder.

Embodiment 2

[0078] Magnolia officinalis 35g, Rhizoma Chuanxiong 38g, Rhizoma Cyperi 25g, Paeoniae Alba 31.5g, Bupleurum 50g, Citrus aurantium 40g, Curcuma 35g, Bergamot 31.5g, Woody 25g, Chenpi 40g, Licorice 24g, Corydalis 50g, Malancao 70g ten The three herbs are used as raw materials;

[0079] The above-mentioned thirteen raw materials were crushed into fine powder passing through a 100-mesh sieve, mixed evenly, 396 g of starch was added, dried at a controlled temperature of 75° C., granulated, and packed into capsules to obtain capsules.

Embodiment 3

[0081] Magnolia officinalis 60g, Chuanxiong 40g, Cyperus cyperi 60g, Baishao 31.5g, Bupleurum 50g, Citrus aurantium 31.4g, Curcuma 20g, Bergamot 25g, Woody 70g, Tangerine peel 31.4g, Licorice 50g, Corydalis 30g, Malancao 100g Thirteen herbs are used as raw materials;

[0082] The above-mentioned thirteen raw materials were crushed into fine powder passing through a 80-mesh sieve, mixed evenly, and 479.44 g of refined honey was added as a binder, mixed evenly, pelletized, dried at a controlled temperature of 55° C., and honeyed pills were obtained.

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Abstract

The invention relates to a medical composition for treating liver disease (that is shu gan shun Qi medical composition) and a preparation method thereof. The medical composition is prepared from 13 crude drugs including Magnolia officinalis, Rhizoma Chuanxiong, Nutgrass Galingale Rhizome, White Peony Root, Chinese Thorowax Root, Fructus Aurantii Immaturus, Aiomatic Turmeric Root-tuber, Fructus Citri Sarcodactylis, Radix Aucklangiae, dried orange peel, licorice, Rhizoma Corydalis Yanhusuo, Kalimeris indica; the basic preparation method comprises the following steps: grinding the raw medicines into fine powder, uniformly mixing the powder, then adding pharmaceutical excipients for uniform mixing, and drying the mixture to obtain the formulation needed. Partial medicinal materials in the composition contain volatile substances, so the invention adopts the steps of firstly crushing 2 / 3 of the raw materials, and then crushing the remaining 1 / 3 of the crude drugs, performing reflux extraction and then decocting to fully utilize effective ingredients, the medicine can be absorbed completely and the medicine efficiency is enhanced. The raw material ratio is screened in a scientific way, and the composition has the effect of smoothing liver, regulating vital energy and alleviating pain, can be used for treating liver depression and qi stagnation symptoms such as rib tumescence, stomach hurt, vomit against the noisy, and belching to realize address both the symptoms and root causes.

Description

technical field [0001] The invention relates to the field of a traditional Chinese medicine composition and its preparation process, more specifically to a medicinal composition for treating liver diseases and a preparation method thereof. Background technique [0002] Bupleurum Shugan Pills are included in "Chinese Pharmacopoeia 2000 Part One" on page 554. The prescription and preparation method are: Poria cocos 100g, Citrus aurantium (fried) 50g, cardamom 40g, white peony root (wine fried) 50g, licorice 50g, fragrant Fu (made from vinegar) 75g, tangerine peel 50g, bellflower 50g, Magnolia officinalis (made from ginger) 50g, hawthorn (fried) 50g, Fangfeng 50g, Liushenqu (fried) 50g, bupleurum 75g, scutellaria baicalensis 50g, mint 50g, perilla stalk 75g, Muxiang 25g, Betel nut (fried) 75g, Sanleng (made with vinegar) 50g, Rhubarb (wine fried) 50g, Qingpi (fried) 50g, Angelica 50g, Jiang Pinellia 75g, Wuyao 50g, Curcuma (made) 50g, above Twenty-five flavors, mixed, crushed ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/14A61K9/48A61P1/16
Inventor 唐德江陈犁
Owner 重庆希尔安药业有限公司
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