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Biological nitrogen, and preparation and use thereof

A technology of biological nitrogen and antibiotics, applied in the direction of biochemical equipment and methods, microorganisms, microorganisms, etc., can solve problems affecting human beings, human body drug resistance, etc., and achieve the effects of easy operation, reduced manufacturing costs, and simple process flow

Inactive Publication Date: 2011-05-04
NORTH CHINA PHARMA GROUP CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the enrichment of antibiotic residues in the animal residues in the fungus feed will affect the human beings themselves and cause the human body to develop drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Example 1: Biological nitrogen was prepared using waste penicillin bacteria residues as raw materials.

[0016] Pour 8 tons of fresh penicillin waste mycelium into the fermentation tank, and let it ferment naturally for 2 hours. Then, pump it into the drum scraper dryer with a mud pump. Mesh sieve grinding to obtain 1 ton of biological protein powder (i.e. biological nitrogen). Its physical properties: protein content 51.2%, soluble phosphorus 8mg / g, water content 7.8%, uniform particle (85% below 50 mesh), yellowish brown, fragrant.

Embodiment 2

[0017] Example 2: Biological nitrogen was prepared by using the waste oxytetracycline residue as raw material.

[0018] Pour 10 tons of fresh oxytetracycline waste mycelium into the fermentation tank, and let it ferment naturally for 4 hours, then put it into the drum scraper dryer with a mud pump, control the temperature at 190-200°C, and dry it continuously for 5-10 seconds. Obtain 1.2 tons of biological protein powder by grinding with a 100-mesh sieve. Physical properties: protein content 50.8%, soluble phosphorus 6mg / g, water content 6.5%, uniform granules (80% below 100 mesh), yellowish brown, fragrant.

Embodiment 3

[0019] Embodiment 3: with vitamin B 12 Bacteria waste residues are used as raw materials to prepare biological nitrogen.

[0020] fresh vitamin B 12 5 tons of waste mycelia were poured into the fermentation tank, and naturally fermented for 8 hours, then pumped into the drum scraper dryer with a mud pump, and the temperature was controlled at 140-150°C, dried instantly, and ground with a 30-mesh sieve to obtain biological nitrogen 0.7 Ton. Physical properties: protein content 48.5%, soluble phosphorus 6mg / g, water content 8.0%, uniform granules (90% below 30 mesh), yellowish brown, fragrant.

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PUM

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Abstract

The invention discloses biological nitrogen, the preparation method thereof and the application thereof. The biological nitrogen takes waste fungi residues generated in the process of producing antibiotic / vitamin as raw materials and is prepared by instant high-temperature drying. The protein content of the biological nitrogen is more than or equal to 45%; the moisture content is less than or equal to 8%; the phosphorus content is 5-10mg / g. The preparation method of the biological nitrogen comprises the following steps: fresh waste fungi residues generated in the process of producing antibiotic / vitamin are poured into a fermentation vat for more than two hours natural fermentation and stirred into mash; b. the mash is instantly dried in high temperature; the temperature is controlled to be within 140-200 DEG C; the drying materials are collected. The prepared biological nitrogen is applied in the same variety of antibiotic / vitamin fermentation medium. The waste fungi residues generated in the process of producing antibiotic / vitamin is reasonably safely applied in the invention; the invention opens up a new application field, establishes an effective, economical cycle production system and provides the technical support for the cleaner production of biological fermentation industries.

Description

technical field [0001] The invention relates to a biological nitrogen and its preparation method and application, in particular to a biological nitrogen which can be used as a new nitrogen source for microbial fermentation and its preparation method and application. Background technique [0002] The current production of antibiotics / vitamins is mainly biosynthesis by microbial fermentation. It needs to consume a large amount of nitrogen sources (such as corn steep liquor, corn gluten meal, peanut cake powder, soybean cake powder, etc.) In China, hundreds of thousands of tons of waste bacteria residues are produced every year due to biological fermentation. Over the years, bio-fermentation waste bacteria residues have been discarded as industrial waste residues. Because the waste bacteria residue contains a large amount of protein, phosphorus, rich vitamins, amino acids and culture medium residues, discarding the waste bacteria residue not only causes a lot of waste of reso...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/00
Inventor 吴梅月吴红云白雪会冯国龙
Owner NORTH CHINA PHARMA GROUP CORP