Injection for treating hyperthyroidism

A technology for injection and hyperthyroidism, which is applied to medical preparations containing active ingredients, endocrine system diseases, cyclic peptide components, etc., can solve the problems of treatment failure, large oral dose, and limitations in clinical promotion, and achieve thyroid volume shrinkage and clinical application. The effect of disappearing symptoms and improving the remission rate

Inactive Publication Date: 2009-07-08
陈小国
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AI Technical Summary

Problems solved by technology

[0006] 4. Thyroid artery interventional embolization treatment: In this treatment, the catheter is sent into the superior thyroid artery through the femoral artery under digital subtraction, and the embolic agent mixed with contrast agent is slowly injected until the blood flow basically stops, and the general embolism area can reach 80 -90%, which is similar to subtotal thyroidectomy. At present, this therapy is still immature clinically. If the em...

Method used

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Embodiment Construction

[0013] A cline injection for treating hyperthyroidism, comprising dexamethasone injection, octreotide injection, and cyclosporine A, the weight ratio of the injection components is: dexamethasone injection: 2-5mg, octreotide injection Solution: 0.5-1mg, cyclosporine A: 10-20mg.

[0014] The best embodiment of the present invention is: dexamethasone injection: 3mg, octreotide injection: 0.6mg, cyclosporine A: 15mg.

[0015] Mechanism of action: one of the medicaments of the present invention, dexamethasone injection, is a glucocorticoid, which has pharmacological effects such as anti-inflammation, anti-virus, suppression of immune response, anti-shock and enhancement of stress response, so it is widely used in various departments to treat various diseases , such as autoimmune diseases, allergies, inflammation, asthma and dermatology, eye diseases. Glucocorticoids such as dexamethasone have no obvious adverse reactions when they are used in physiological dose replacement therap...

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Abstract

The invention relates to an injection medicament for treating hyperthyroid, which comprises the following components by weight part: 2 to 5 milligrams of dexamethasone injection, 0.5 to 1 milligram of octreotide injection, and 10 to 20 milligrams of ciclosporin A. Immune preparations such as the dexamethasone injection, the octreotide injection, the ciclosporin A and the like are adopted for treating the hyperthyroid by locally injecting the thyroid, the volume of the tumid thyroid is remarkably shrunk, and the function of the thyroid basically recovers within two months, so the injection medicament has remarkable curative effect, and can remarkably improve the remission rate of hyperthyroid and reduce the rate of relapse. Serious abnormal change, hypothyroidism and parathyroid hypofunction are not caused, and laryngeal recurrent nerve injury is also not caused. Through more than 580 cases of clinical therapy in related hospitals, the volume of the tumid thyroid is remarkably shrunk after therapy, clinical symptoms disappear, allergic response and complications are not caused, the effective percentage is nearly 100 percent, and the cure rate is as high as 98 percent.

Description

technical field [0001] The invention relates to a Keyingsu injection for treating hyperthyroidism. Background technique [0002] Toxic diffuse goiter with hyperthyroidism, referred to as hyperthyroidism, is an autoimmune disease. Currently, there are several ways to treat hyperthyroidism: [0003] 1. Antithyroid drug (methimazole or propylthiouracil) treatment: insist on taking it for a long time, at least 1.5 to 2 years. The course of treatment is long, the remission rate is about 40-60%, and the recurrence rate is high. In the course of treatment, it is easy to cause liver function damage and agranulocytosis. Once agranulocytosis occurs, measures should be taken immediately, otherwise, severe infection may cause death. If liver function is impaired, transaminases and jaundice index increase, liver protection treatment should be strengthened. Therefore, changes in blood routine and liver function should be monitored regularly during medication. There are also individual...

Claims

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Application Information

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IPC IPC(8): A61K38/13A61P5/16A61K38/12A61K31/573
Inventor 陈小国张玉平
Owner 陈小国
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