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Spectroscopy measurements

A detection area and light transmission technology, applied in the field of spectroscopy measurement, can solve the problems of prone to errors, reduced measurement accuracy, and simple relationships are no longer effective, and achieve the effect of strong adaptability

Inactive Publication Date: 2009-11-04
KONINK PHILIPS ELECTRONICS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in transmission or diffuse reflectance spectroscopy on turbid media (such as human skin), the simple relationship of the Lambert-Beer law is no longer valid
Linear regression analysis of the spectrum of turbid media is prone to error, resulting in a significant loss of measurement accuracy

Method used

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Examples

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Embodiment Construction

[0044] The invention is based on the use of a spatial light modulator to define a light transmission pattern by applying a corresponding electric field to the electrodes of the modulator. The plate including the electrodes should be transparent in the wavelength range considered. According to an embodiment, the electrodes of the modulator may be manipulated such that in the considered wavelength range some parts of the modulator are transparent and other parts are opaque to define said light transmission pattern.

[0045]In this specification, for the sake of convenience, devices will be described with reference to lower and upper positions. These positions do not mean that the device cannot be otherwise positioned, but rather allow for easier description of the elements. These locations are figure 2 the location of the device. The lower part is the part on the skin side.

[0046] According to the first embodiment of the present invention, and with reference to figure 1 ...

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Abstract

The invention relates to a device and method for the measurement of the concentration of at least one substance in a turbid medium. The device comprises at least one radiation source (12) adapted to illuminate the turbid medium (17) on at least one irradiation area. The device further comprises at least one detector adapted to detect backscattered light from the turbid medium from at least one detection area and to generate detection signals representative of the backscattered light. The device is arranged to generate detection signals with respect to at least two different irradiation- detection distances. The irradiation-detection distances are defined as the respective distances between the irradiation areas and the detection areas. The device also comprises at least one spatial light modulator (2), comprising at least two electrode plates (5, 8) enclosing a liquid (7), the electrode plates supporting a plurality of electrodes (6, 10) arranged to define, with the liquid (7), light transmission patterns depending on the electrical field between the electrodes (6, 10), the irradiation areas and / or the detection areas being defined by said light transmission patterns.

Description

technical field [0001] The invention relates to the spectroscopic measurement of the concentration of a substance in a scattering medium. In particular, the present invention relates to devices and methods for non-invasively monitoring the concentration of glucose in human blood. Background technique [0002] Spectroscopy can be used to measure the concentration of substances in human skin. A beam of light is sent onto the skin and the light interacting with the medium (backscattered or transmitted) is detected in order to measure the reflectance of the probed skin volume. An absorption spectrum is derived from the reflectivity, and the concentration of the target substance is calculated from this absorption spectrum by means of a mathematical model using the known spectral properties of the substance contained in the medium. On-skin spectroscopy allows in vivo and non-invasive estimation of analyte concentrations in human blood. [0003] The basic idea of ​​quantitative ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
CPCA61B5/14558
Inventor W·伦森L·P·巴克
Owner KONINK PHILIPS ELECTRONICS NV