Dry extracts of pelargonium sidoides and pelargonium reniforme

Abstract

The invention relates to production methods for obtaining dry extracts from Pelargonium sidoides and / or Pelargonium reniforme, extracts obtainable according to said method, and pharmaceutical productscomprising such extracts.

Description

technical field [0001] The present invention relates to a process for the preparation of dry extracts obtained from Pelargonium angustiflora and / or Pelargonium nephrifolia, the extracts obtained by said process and preparations containing these extracts. Background technique [0002] Preparations obtained from the Pelargonium species Pelargonium angustifolia and / or Pelargonium nephrifolia native to South Africa are traditionally used in this area for the therapeutic treatment of respiratory disorders and gastrointestinal symptoms. [0003] The efficacy of a hydroalcoholic liquid extract of the root of Pelargonium angustifolia (EP 7630) for the treatment of respiratory infections and the ENT area has been confirmed by numerous clinical studies and practical observations at the same time (Kolodziej et al., Deutsche Apotheker Zeitung 143(12) : 55-64 (2003)). [0004] The action of the extract is facilitated by a variety of therapeutically active ingredients. Tanning agents an...

AI Technical Summary

Problems solved by technology

[0009] However, we also faced a problem in the preparation of Pelargonium dry extract that the dry extract obtained by directly drying the Pelargonium liquid extract is not completely dissolved in a physiologically compatible solvent even when the solvent is in a large excess, The solvent is primarily an aqueous solvent and or an aqueous alcoholic solvent (including mixtures of water and polyols and optionally alcohols) (see Comparative Examples 1-2)

On the one hand, this makes it difficult to prepare liquid formulations from these dry extracts, while on the other hand the potency of dry extracts in general may also be compromised