Cervical mucosa inducing gel

A mucous membrane and gel technology, which is applied in the directions of non-active medical preparations, peptide/protein components, sexual diseases, etc., to achieve extensive killing and inhibition, transparent and beautiful appearance, and improved bioavailability.

Inactive Publication Date: 2010-04-07
杨霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this literature does not provide a kind of medicine that can be used clinically, and is effective to the treatment of common cervicitis and cervical erosion

Method used

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  • Cervical mucosa inducing gel
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  • Cervical mucosa inducing gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Example 1, a gel for treating inflammatory diseases of the cervix, the ingredients include carbomer, triclosan and human epidermal growth factor (human Epidermal Growth Factor, hEGF or rhEGF), taking one kilogram as an example , the carbomer concentration is 3%, that is, every kilogram of gel contains 30g to carbomer; every kilogram of gel contains triclosan 6g, human epidermal growth factor (contains hEGF0.1mg human epidermal growth factor in every kilogram of gel) factor). The specific method is to add 30g of carbomer into 1 liter of purified water, and use a high-speed disperser to fully dissolve it. At the same time, 6 g of triclosan was fully dissolved in 5 ml of NaOH solution with a mass concentration of 20%. Add the dissolved triclosan into 1 liter of fully dissolved carbomer solution, and continue to stir to make it evenly mixed. The pH value of the product is adjusted to between 7.0 and 7.5 with a NaOH solution having a mass concentration of 20%, and the prod...

Embodiment 2

[0057] Example 2, a gel for treating inflammatory diseases of the cervix, the ingredients include carbomer, triclosan and human epidermal growth factor (human Epidermal Growth Factor, hEGF), taking one kilogram as an example, carb The concentration of carbomer is 5%, that is, 50 g carbomer is contained in every kilogram of gel; 1 g of triclosan and human epidermal growth factor are contained in every kilogram of gel (1 mg human epidermal growth factor of hEGF is contained in every kilogram of gel). The specific method is to add 50g of carbomer into 1 liter of purified water, and use a high-speed disperser to fully dissolve it. At the same time, 1 g of triclosan was fully dissolved in 5 ml of NaOH solution with a mass concentration of 10%. Add the dissolved triclosan into 1 liter of fully dissolved carbomer solution, and continue to stir to make it evenly mixed. The pH value of the product is adjusted to between 7.0 and 7.5 with a NaOH solution having a mass concentration of 1...

Embodiment 3

[0058] Example 3, a gel for treating inflammatory diseases of the cervix, the ingredients include Carbomer, Triclosan and human epidermal growth factor (human Epidermal Growth Factor, hEGF), taking one kilogram as an example, the calorie The concentration of carbomer is 4%, that is, 40g carbomer is contained in every kilogram of gel; 3.5g of triclosan and human epidermal growth factor are contained in every kilogram of gel (containing hEGF0.6mg human epidermal growth factor in every kilogram of gel) . The specific method is to add 40g of carbomer into 1 liter of purified water, and use a high-speed disperser to fully dissolve it. At the same time, 3.5 g of triclosan was fully dissolved in 5 ml of NaOH solution with a mass concentration of 30%. Add the dissolved triclosan into 1 liter of fully dissolved carbomer solution, and continue to stir to make it evenly mixed. The pH value of the product is adjusted to between 7.0 and 7.5 with a NaOH solution having a mass concentratio...

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PUM

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Abstract

The invention relates to a gel which can improve vaginal microenvironment and restore vaginal microdamage and is suitable for treatment on various kinds of vaginitis and cervicitis caused by vaginal microecological disturbance and vaginal microdamage, auxiliary treatment on vaginitis and cervicitis after clinical treatment, and treatment on cervical erosion, in particular to a cervical mucosa inducing gel which comprises carbomer, triclosan and human epidermal growth factors, wherein the concentration of the carbomer is 3%-5%, the concentration of the triclosan is 0.1%-0.6%, and the concentration of the human epidermal growth factors is 1/100000-1/10000. The cervical mucosa inducing gel can effectively improve the vaginal cleanness and increase the lactobacillus quantity to further reduce the vaginal pH value, has obvious effect on restoring cervical erosion, and can be used for auxiliary treatment on vaginitis and cervicitis after treatment.

Description

technical field [0001] The invention relates to a gel, which can improve vaginal microenvironment and repair vaginal microdamage. It is suitable for all kinds of vaginitis and cervicitis caused by vaginal microecological imbalance and vaginal micro-injury, and it is suitable for adjuvant treatment after clinical treatment of vaginitis and cervicitis and treatment of cervical erosion. Specifically, it is a cervical mucosa induction gel. Background technique [0002] Vaginitis is a common disease in gynecological outpatient clinics, frequently-occurring, and its incidence is mostly related to the imbalance of vaginal microecology, and the treatment effect is poor, and the recurrence rate is high. For the treatment of vaginal inflammation, anti-inflammatory treatment is often used, and a large number of antibiotics and bactericides are more likely to cause flora imbalance. [0003] There are many kinds of microbial flora in the vagina of healthy women, mainly Lactobacillus, S...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/18A61K9/00A61K47/32A61P15/00A61P15/02A61K31/085
Inventor 杨霞
Owner 杨霞
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