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Aruncus dioicus extractive with function of antibacterial activity

A technology of false cohosh root and antibacterial activity, applied in the field of research and development of pharmaceutical products

Inactive Publication Date: 2011-11-09
SHANDONG UNIV AT WEIHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many reports about food poisoning caused by Staphylococcus aureus at home and abroad

Method used

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  • Aruncus dioicus extractive with function of antibacterial activity
  • Aruncus dioicus extractive with function of antibacterial activity
  • Aruncus dioicus extractive with function of antibacterial activity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] (1) Take the roots of False Cohosh, remove impurities, wash with water, dry or air-dry, crush, extract with 10 times the amount of 85% ethanol at room temperature for 6 hours, and then ultrasonically for 1.5 hours at 30°C and 80W power, Then filter once respectively with silk cloth and filter paper to obtain the filtrate;

[0017] (2) the filter residue after the treatment of False Cimicifuga root through (1) repeats (1) step each once again with 6 times of amount and 4 times of amount of 85% ethanol respectively, obtains filtrate respectively, merges three times of filtrate;

[0018] (3) Recover the ethanol from the above-mentioned (2) filtrate to obtain the root extract of Pseudomonas cohosh with a yield of 25%.

Embodiment 2

[0020] (1) Take the root of False Cimicifuga, remove impurities, wash with water, dry or dry in the air, crush, extract with 8 times the amount of 75%% ethanol at room temperature for 4 hours, and then ultrasonicate for 1 hour at a temperature of 30°C and a power of 80W. Then filter once respectively with silk cloth and filter paper to obtain the filtrate;

[0021] (2) the filter residue after the treatment of False Cimicifugae root through (1) repeats (1) step each once again with 6 times of amount and 4 times of amount of 75% ethanol respectively, obtains filtrate respectively, merges three times of filtrate;

[0022] (3) Recover the ethanol from the above-mentioned (2) filtrate to obtain the root extract of False Cimicifuga with a yield of 22%.

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Abstract

The invention belongs to the technical field of research and development of medical products, and relates to an aruncus dioicus extractive with the function of antibacterial activity prepared by aruncus (Aruncus sylvesterKostel.ex Maxim.). The product has good antibacterial effect to five common pathogenic bacterium and food putrefying bacteria such as staphylococcus aureus. The restriction effects of staphylococcus aureus, salmonella, colon bacillus, streptococcus to bacillus subtilis are gradually decreased. The product can be developed into natural antimicrobial applied to the industries of food, medicine, and the like to prepare products with various forms with the antibacterial function.

Description

technical field [0001] The invention belongs to the technical field of research and development of pharmaceutical products. The invention relates to the preparation of the root extract of Aruncus sylvester Kostel.ex Maxim. with antibacterial activity by using the root of Aruncus sylvesterKostel.ex Maxim. Background technique [0002] The false cohosh root extract of the present invention has good bacteriostatic effect on 5 kinds of common pathogenic bacteria such as staphylococcus aureus and food spoilage bacteria, and this antibacterial effect has positive application value, which is helpful for expanding the Drug sources, and their rational development and utilization are of great significance. [0003] Staphylococcus aureus is a gram-positive bacterium, which is the most pathogenic bacterium among staphylococci. It is widely distributed in nature and can often cause purulent inflammation of the skin, tissues and organs. The toxin it produces enters the human intestinal t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61P31/04A23L1/29A23L1/28A61K125/00A23L33/105
CPCY02A50/30
Inventor 张崇禧
Owner SHANDONG UNIV AT WEIHAI