Chinese medicinal ointment with antibacterial and antipruritic effects and preparation method thereof

A technology of ointment and traditional Chinese medicine, applied in the field of preparation of the ointment, can solve the problems of pigmentation on the skin, difficulty and inconvenience for children to take, and achieve the effects of safe and reliable clinical application, fast onset of action and obvious pharmacological effect.

Active Publication Date: 2010-06-09
CHENGDU YONGKANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently marketed drugs for the treatment of this disease either contain hormone ingredients, or have the disadvantage of causing pigmentation on the skin after use; or only for the acute phase, or only for the chronic phase; or the drugs are oral preparations, which are difficult for children to take and inconvenience

Method used

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  • Chinese medicinal ointment with antibacterial and antipruritic effects and preparation method thereof
  • Chinese medicinal ointment with antibacterial and antipruritic effects and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The preparation method 1 of embodiment 1 ointment of the present invention

[0014] 1. Formula composition:

[0015] Composition of main drug raw materials: Phellodendron 500g, Sophora flavescens 500g, Duckweed 500g, Aloe vera 100g, Artemisia argyi 500g, Nepeta 500g, Borneol 50g

[0016]Excipient composition: cetyl alcohol 2100g, vaseline 2100g, glycerin 990ml, sodium lauryl sulfate 85g, 0.1% sodium benzoate 10g

[0017] 2. Preparation method:

[0018] 1) Preparation of the aqueous phase:

[0019] Weigh cork cortex, flavescens, and duckweed of the formula amount, add water and decoct three times, add 12 times the amount of water for the first time, soak for 1hr, add 10 times the amount of water for the second and third times, decoct for 0.5hr each time, Centrifuge and filter while hot, combine the filtrates, concentrate under reduced pressure until the relative density is 1.02-1.03 (measured at 50-60°C), add the aloe fine powder of the formula amount, stir to dissolv...

Embodiment 2

[0024] Embodiment 2 The preparation method 2 of ointment of the present invention

[0025] 1. Formula composition:

[0026] Composition of main drug raw materials: Phellodendron 400g, Sophora flavescens 400g, Duckweed 400g, Aloe vera 80g, Artemisia argyi 400g, Nepeta 400g, Borneol 40g

[0027] Excipient composition: cetyl alcohol 1680g Vaseline 1680g glycerin 792ml sodium lauryl sulfate 68g 0.1% sodium benzoate 8g

[0028] 2. Preparation method:

[0029] 1) Preparation of the aqueous phase:

[0030] Weigh cork cortex, flavescens, and duckweed of the formula amount, add water and decoct three times, add 12 times the amount of water for the first time, soak for 1hr, add 10 times the amount of water for the second and third times, decoct for 0.5hr each time, Centrifuge and filter while hot, combine the filtrates, concentrate under reduced pressure until the relative density is 1.02-1.03 (measured at 50-60°C), add the aloe fine powder of the formula amount, stir to dissolve, ad...

Embodiment 3

[0034] Embodiment 3 The preparation method 3 of ointment of the present invention

[0035] 1. Formula composition:

[0036] Composition of main drug raw materials: Phellodendron 600g, Sophora flavescens 600g, Duckweed 600g, Aloe vera 120g, Artemisia argyi 600g, Nepeta 600g, Borneol 60g

[0037] Excipient composition: cetyl alcohol 2520g Vaseline 2520g glycerin 1188ml sodium lauryl sulfate 102g 0.1% sodium benzoate 12g

[0038] 2. Preparation method:

[0039] 1) Preparation of the aqueous phase:

[0040] Weigh cork cortex, flavescens, and duckweed of the formula amount, add water and decoct three times, add 12 times the amount of water for the first time, soak for 1hr, add 10 times the amount of water for the second and third times, decoct for 0.5hr each time, Centrifuge and filter while hot, combine the filtrates, concentrate under reduced pressure until the relative density is 1.02-1.03 (measured at 50-60°C), add the aloe fine powder of the formula amount, stir to dissolve...

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Abstract

The invention discloses a Chinese medicinal ointment with antibacterial and antipruritic effects and a preparation method thereof. The Chinese medicinal ointment comprises the following raw materials: amur corktree bark, lightyellow sophora root, common ducksmeat herb, aloe, argy wormwood leaf, fineleaf schizonepeta herb, borneol and the like. The invention also discloses a preparation method forthe Chinese medicinal ointment, which comprises the following steps: preparing a water phase from the amur corktree bark, the lightyellow sophora root, the common ducksmeat herb and the aloe; collecting volatile oil from the argy wormwood leaf and the fineleaf schizonepeta herb; grinding the borneol into fine powder; preparing an oil phase from cetyl alcohol, vaseline and glycerin; and preparing the ointment by normal working procedures. When the Chinese medicinal ointment is prepared, a water decoction heat filter method and a steam distillation method are respectively adopted to make effective medicaments give full play. When used, the Chinese medicinal ointment has the characteristics that the medicaments are directly acted on disease positions; and the response is quick. The ointment of the invention has good antibacterial, anti-inflammatory and antipruritic effects and is in a dose-response relationship. The long-term toxicity research proves that the Chinese medicinal ointment is safe.

Description

field of invention [0001] The invention relates to a traditional Chinese medicine ointment, in particular to a traditional Chinese medicine ointment with antibacterial and antipruritic effects, and also relates to a preparation method of the ointment. Background technique [0002] Eczema can be divided into acute, subacute, and chronic, which is equivalent to the category of "eczema" in Chinese medicine. It has the characteristics of pleomorphic damage, symmetrical distribution, conscious itching, recurrent attacks, and easy evolution into chronic diseases. Because of its frequent recurrence, treatment is very difficult. [0003] Traditional Chinese medicine believes that the onset of the disease is mostly caused by the intolerance of congenital endowment, wind, damp and heat resistance on the skin. The acute ones are mainly damp and hot, the subacute ones are mostly related to spleen deficiency and nostalgia for damp pathogens, and the chronic ones are caused by blood dama...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/06A61K47/20A61P17/00A61P17/04A61K31/045
Inventor 牛锐
Owner CHENGDU YONGKANG PHARM CO LTD
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