A kind of preparation method of micron polymethyl methacrylate microsphere

A polymethyl methacrylate, micron-scale technology, applied in the field of biomedical materials, achieves the effect of simple operation process and mild implementation conditions
CN101787138BActive Publication Date: 2012-02-15广东天昊药业有限公司
0 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
广东天昊药业有限公司
Publication Date
2012-02-15

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention provides a method for preparing monodisperse micron-sized polymethyl methacrylate microspheres, which uses polymethyl methacrylate as a raw material, polyvinyl alcohol solution as a dispersion medium, and is prepared by an emulsion dispersion solvent volatilization method. Under high-speed stirring, PMMA solution is added to the aqueous solution of polyvinyl alcohol at a certain flow rate to form a uniform and stable emulsion. After ultrasonic dispersion, solvent volatilization, suction filtration, water washing, vacuum drying, etc. Regular, non-adhesive microspheres. The particle diameter of the microsphere is 10-100 μm, and the particle size and particle size distribution can be controlled. Compared with the prior art, the invention has the advantages of simple operation process and mild implementation conditions, and provides a simple and feasible new method for preparing monodisperse and micron-sized polymethyl methacrylate microspheres. The obtained polymethyl methacrylate microspheres can be used in the fields of biomedical materials such as drug carriers, bone repair, orthopedic materials.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of biomedical materials, in particular to a preparation method of micron-sized polymethyl methacrylate microspheres. Background technique

[0002] Polymethyl methacrylate (PMMA) is the most important and most commonly used material in acrylates. It has excellent performance and a wide range of uses. It has become one of the plastic products widely used in various sectors of the national economy. Polished PMMA is widely used in the production of medical utensils, transparent covers of medical equipment (such as incubators, operation boxes, etc.), observation mirrors, surgical tools, etc. Because PMMA has good compatibility with human tissue, is non-toxic to human body, has good light transmittance, stable chemical properties, and is easy to process into the desired shape, so PMMA can be used in medicine to make artificial corneas, orthopedic bonding and fixed joint prostheses. Body, bone cement, dentures, dentures, mo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More