Use of CLEC1B for the determination of cardiovascular and thrombotic risk
A cardiovascular and thrombosis technology, applied in the application field of CLEC1B for identifying cardiovascular and thrombosis risks, and can solve problems such as cardiac tissue damage
Inactive Publication Date: 2010-08-18
SANOFI AVENTIS SA
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As a result, the patient or attending physician is often unaware of possible d...
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The use of the single nucleotide polymorphism (SNP) of the CLEC1B gene for the identification of cardiovascular and/or thrombotic disorders or of an increased risk for developing cardiovascular and/or thrombotic disorders in a biological sample taken from an individual to be examined; the use of CLEC1B for identifying substances active in preventing and/or treating cardiovascular and/or thrombotic disorders and methods for doing so.
Description
Use of CLEC1B to identify cardiovascular and thrombotic risk technical field The present invention relates to the use of single nucleotide polymorphisms (SNPs) and protein polymorphisms in identifying increased risk of cardiovascular and / or thrombotic disorders and primers and nucleic acids suitable for said use. Furthermore, the present invention relates to the discovery of CLEC1B (C-type lectin domain family 1, member B or alternatively C-type lectin-like receptor 2 / CLEC-2, hereinafter referred to as CLEC1B) for the prevention and treatment of cardiovascular and use in active substances for thrombotic disorders. Background technique Cardiovascular and / or thrombotic disorders are among the leading causes of death in both sexes in Western countries. Cardiovascular disorders include all disorders affecting the function of the heart, including in particular cardiac tissue and cardiovascular disorders. Thrombotic disorders include all pathological conditions affecting blood...
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CPCG01N2800/52C12Q1/6883G01N2800/50G01N2333/7056C12Q2600/136C12Q2600/106G01N2500/04G01N33/566G01N2800/32C12Q2600/156A61P9/00A61P9/10A61P9/12C12Q1/6897
Inventor D·科齐安P·沃内罗M·赫尔曼
Owner SANOFI AVENTIS SA
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