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Vitamin water aqua and preparation method thereof

A technology of vitamins and fat-soluble vitamins, which is applied in the direction of pharmaceutical formulas, additional food elements, and medical preparations containing active ingredients, etc., can solve problems such as unstable process of water preparations, few active ingredients, and complexity, so as to avoid loss and use Insufficient rate, enhanced disease resistance, and stable storage properties

Active Publication Date: 2013-07-03
DINGZHENG XINXING BIOTECH TIANJIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently known methods have the disadvantages of less effective ingredients in the water preparation, instability of the water preparation and complex processes

Method used

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  • Vitamin water aqua and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A kind of preparation method of vitamin water preparation comprises the following steps:

[0031] (1) Preparation of liposomes

[0032] Mix 10g of soybean lecithin and 5g of cholesterol and add to the reaction kettle, the reaction time is 30-45min, and the reaction temperature is 20°C;

[0033] (2) Preparation of fat-soluble vitamin solution

[0034] Dissolve 11000000IU (3.78g) vitamin A, 160000000IU (4g) vitamin D, 2000IU (2g) vitamin E, 1000IU (1g) vitamin K, 10g polyethylene glycol 6000 and 5g polyvinylpyrrolidone in the organic solvent chloroform and ethanol (The weight ratio of chloroform and ethanol is 2: 1) in the mixed solution, makes fat-soluble vitamin solution;

[0035] (3) Preparation of water-soluble vitamin solution

[0036] Dissolve 4g of vitamin B1, 4g of vitamin B2, 2g of vitamin B6, 2g of vitamin B12, 4g of vitamin C, 2g of vitamin H, and 2g of folic acid in PBS buffer with a pH value of 6.0, and the temperature of the buffer is 30°C to obtain a wat...

Embodiment 2

[0043] A kind of preparation method of vitamin water preparation comprises the following steps:

[0044] (1) Preparation of liposomes

[0045] Mix 10g of soybean lecithin, 20g of sorbitol and 5g of cholesterol into the reactor, the reaction time is 3045min, and the reaction temperature is 65°C;

[0046] (2) Preparation of fat-soluble vitamin solution

[0047] Dissolve 5500000IU (1.89g) vitamin A, 160000000IU (4g) vitamin D, 2000IU (2g) vitamin E, 1000IU (1g) vitamin K, 10g polyethylene glycol 6000 and 5g polyvinylpyrrolidone in the organic solvent chloroform and ethanol (The weight ratio of chloroform and ethanol is 2: 1) in the mixed solution, makes fat-soluble vitamin solution;

[0048] (3) Preparation of water-soluble vitamin solution

[0049] Dissolve 4g of vitamin B1, 2g of vitamin B2, 2g of vitamin B6, 1g of vitamin B12, 6g of vitamin C, 2g of vitamin H, and 2g of folic acid in PBS buffer with a pH value of 7.4, and the temperature of the buffer is 45°C to obtain a wa...

Embodiment 3

[0056] A kind of preparation method of vitamin water preparation comprises the following steps:

[0057] (1) Preparation of liposomes

[0058] Mix 5g of soybean lecithin, 5g of distearoylphosphatidylcholine, 20g of sorbitol and 5g of cholesterol and add them into the reaction kettle. The reaction time is 30-45min, and the reaction temperature is 55°C;

[0059] (2) Preparation of fat-soluble vitamin solution

[0060] Dissolve 11000000IU (3.78g) vitamin A, 160000000IU (4g) vitamin D, 2000IU (2g) vitamin E, 2000IU (2g) vitamin K, 10g polyethylene glycol 6000 and 5g polyvinylpyrrolidone in the organic solvent chloroform and ethanol (The weight ratio of chloroform and ethanol is 2: 1) in the mixed solution, makes fat-soluble vitamin solution;

[0061] (3) Preparation of water-soluble vitamin solution

[0062] Dissolve 4g of vitamin B1, 2g of vitamin B2, 6g of vitamin B6, 2g of vitamin B12, 4g of vitamin C, 2g of vitamin H, and 2g of folic acid in PBS buffer with a pH value of 7.0,...

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Abstract

An aqueous formulation of vitamins and the preparation method thereof. Based on the weight, the raw material composition of the aqueous formulation includes: liposomes, 1.89~5.85 parts vitamin A, 2~4 parts vitamin D, 1~3 parts vitamin E, 1~2 parts vitamin K, 4~6 parts vitamin B1, 2~4 parts vitamin B2, 2~6 parts vitamin B6, 1~2 parts vitamin B12, 1~6 parts vitamin C, 2~4 parts vitamin H, 1~2 parts folic acid, and solubilizers.

Description

technical field [0001] The invention belongs to a vitamin additive in animal aquaculture technology, in particular to a vitamin water preparation and a preparation method thereof. Background technique [0002] Vitamin is an organic substance necessary for the body to maintain normal functions, but it cannot be synthesized in the body, or the amount of synthesis is very small, and it needs to be ingested through food. Vitamins play an important role in regulating the body's substance metabolism and maintaining physiological functions. It mainly participates in various chemical reactions in the body's metabolism in the form of coenzymes and catalysts, so as to ensure the normal cell structure and function of the body's tissues and organs. To maintain the normal daily health and various activities of animals, the lack of vitamins can cause metabolic disorders in the body, affecting animal health and normal biological activities. [0003] Vitamins can be divided into fat-solubl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16
CPCA61K9/127A23D7/011A23K1/164A23K1/1603A61K31/51A23D9/013A61K31/714A23K20/158A23K20/174A61P3/02
Inventor 刘鼎阔郭立力王立红董惠峰张勇张凤洪张俊霞
Owner DINGZHENG XINXING BIOTECH TIANJIN
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